Sun Wenhao, Schnell Melanie
Deutsches Elektronen-Synchrotron DESY, Notkestr. 85, 22607 Hamburg, Germany.
Institute of Physical Chemistry, Christian-Albrechts-Universität zu Kiel, Max-Eyth-Strasse 1, 24118 Kiel, Germany.
J Phys Chem Lett. 2023 Aug 24;14(33):7389-7394. doi: 10.1021/acs.jpclett.3c01900. Epub 2023 Aug 11.
Since the first experimental implementation in 2013, microwave three-wave mixing has emerged as a robust spectroscopic approach for analyzing and controlling chiral molecules in the gas phase. This resonant, coherent, and nonlinear technique is based on the three-dimensional light-matter interaction in the electric dipole approximation, allowing for isomer- and conformer-selective chiral analysis with high resolution. Here we demonstrate the utility of microwave three-wave mixing for analyzing a molecular complex, limonene-HO, which serves as a compelling example of addressing its potential to improve the chiral sensitivity for only weakly polar chiral molecules. The use of molecular complexes can also extend the applicability of microwave three-wave mixing to chiral systems that are not in the point group.
自2013年首次实验实现以来，微波三波混频已成为一种用于分析和控制气相手性分子的强大光谱方法。这种共振、相干和非线性技术基于电偶极近似下的三维光与物质相互作用，能够实现高分辨率的异构体和构象体选择性手性分析。在此，我们展示了微波三波混频在分析分子复合物柠檬烯-HO中的应用，该复合物是提高仅弱极性手性分子手性灵敏度潜力的一个有说服力的例子。分子复合物的使用还可以将微波三波混频的适用性扩展到不属于 点群的手性系统。
