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急性角膜葡萄膜炎伴角膜移植片溶解作为轻度化学烧伤的晚期并发症,可能与新型冠状病毒肺炎感染相关:一例报告

ACUTE KERATOUVEITIS WITH CORNEAL GRAFT MELTING AS A LATE COMPLICATION OF MILD CHEMICAL BURN POTENTIALLY ASSOCIATED WITH COVID-19 INFECTION: A CASE REPORT.

作者信息

Majtánová N, Kurilová V, Krišková P, Kéri P, Fellner Z, Cholevík D, Majtán J, Kolář P

出版信息

Cesk Slov Oftalmol. 2023 Spring;79(4):192-200. doi: 10.31348/2023/25.

Abstract

UNLABELLED

Chemical burns are sight-threatening injuries that require immediate management. The main goal of the initial treatment is prompt and copious irrigation to neutralize and eliminate the chemical, followed by various therapeutic options (conservative and surgical) according to the individual patient's postinjury findings.

PURPOSE

In this case report, we describe the course and treatment of a patient with chemical alkali burns of both eyes. This study reports the outcomes of an ocular alkali burn patient who became infected with COVID-19 and where severe keratouveitis with corneal graft melting and hypopyon occurred, ultimately resulting in evisceration of the eye.

OBSERVATIONS

We report the case of a 35-year-old woman, after an alkali burn of both eyes. Complete re-epithelialization of both corneas occurred within three weeks. Due to this observation, we assumed a satisfactory healing prognosis. However, corneal lysis occurred in the left eye over time. The condition was managed, but subsequently severe keratouveitis with hypopyon and corneal lysis occurred in the left eye, apparently in connection with the COVID-19 infection, which ultimately led to the evisceration of the affected eye.

CONCLUSIONS AND IMPORTANCE

In the case report, we describe the management of a mild chemical alkali burn of the right eye and a complicated moderate burn of the left eye with an alkaline chemical. Both eyes were completely healed within three weeks. However, the findings on the left eye became complicated, which ultimately led to the evisceration of the affected eye. The disease of COVID-19 could have contributed to the deterioration of the findings on the cornea, or it could have just been a coincidence of two diseases, with the keratouveitis having a serious course due to the previous difficult course of healing and many complications after the chemical burn.

摘要

未标注

化学烧伤是威胁视力的损伤,需要立即处理。初始治疗的主要目标是迅速大量冲洗以中和并清除化学物质,随后根据个体患者伤后的情况采取各种治疗方案(保守治疗和手术治疗)。

目的

在本病例报告中,我们描述了一名双眼化学性碱烧伤患者的病程及治疗情况。本研究报告了一名眼部碱烧伤患者感染新型冠状病毒肺炎(COVID-19)后发生严重角膜葡萄膜炎伴角膜移植溶解和前房积脓,最终导致眼球摘除的结果。

观察结果

我们报告了一名35岁女性双眼碱烧伤后的病例。双眼角膜在三周内完全重新上皮化。基于这一观察结果,我们认为愈合预后良好。然而,随着时间推移,左眼发生了角膜溶解。病情得到了处理,但随后左眼出现了伴有前房积脓和角膜溶解的严重角膜葡萄膜炎,显然与COVID-19感染有关,最终导致患眼眼球摘除。

结论及重要性

在本病例报告中,我们描述了右眼轻度化学性碱烧伤和左眼碱性化学物质所致复杂中度烧伤的处理情况。双眼在三周内完全愈合。然而,左眼的情况变得复杂,最终导致患眼眼球摘除。COVID-19疾病可能导致了角膜情况的恶化,也可能只是两种疾病的巧合,由于之前愈合过程困难且化学烧伤后有许多并发症,角膜葡萄膜炎病情严重。

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