Ergenekon Almala Pinar, Gokdemir Yasemin, Ersu Refika
Division of Pediatric Pulmonology, Marmara University, 34890 Istanbul, Turkey.
Division of Respirology, Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1N 6N5, Canada.
J Clin Med. 2023 Jul 30;12(15):5022. doi: 10.3390/jcm12155022.
Obstructive sleep apnea (OSA) is characterized by recurrent complete or partial obstruction of the upper airway. The prevalence is 1-4% in children aged between 2 and 8 years and rising due to the increase in obesity rates in children. Although persistent OSA following adenotonsillectomy is usually associated with obesity and underlying complex disorders, it can also affect otherwise healthy children. Medical treatment strategies are frequently required when adenotonsillectomy is not indicated in children with OSA or if OSA is persistent following adenotonsillectomy. Positive airway pressure treatment is a very effective modality for persistent OSA in childhood; however, adherence rates are low. The aim of this review article is to summarize medical treatment options for OSA in children.
阻塞性睡眠呼吸暂停(OSA)的特征是上呼吸道反复出现完全或部分阻塞。2至8岁儿童的患病率为1%-4%,且由于儿童肥胖率上升而呈上升趋势。虽然腺样体扁桃体切除术后持续性OSA通常与肥胖及潜在的复杂疾病有关,但它也可能影响原本健康的儿童。当OSA患儿不适合进行腺样体扁桃体切除术或腺样体扁桃体切除术后仍存在OSA时,通常需要采取药物治疗策略。气道正压通气治疗是儿童持续性OSA的一种非常有效的治疗方式;然而,依从率较低。这篇综述文章的目的是总结儿童OSA的药物治疗选择。