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儿童阻塞性睡眠呼吸暂停的医学治疗

Medical Treatment of Obstructive Sleep Apnea in Children.

作者信息

Ergenekon Almala Pinar, Gokdemir Yasemin, Ersu Refika

机构信息

Division of Pediatric Pulmonology, Marmara University, 34890 Istanbul, Turkey.

Division of Respirology, Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON K1N 6N5, Canada.

出版信息

J Clin Med. 2023 Jul 30;12(15):5022. doi: 10.3390/jcm12155022.

Abstract

Obstructive sleep apnea (OSA) is characterized by recurrent complete or partial obstruction of the upper airway. The prevalence is 1-4% in children aged between 2 and 8 years and rising due to the increase in obesity rates in children. Although persistent OSA following adenotonsillectomy is usually associated with obesity and underlying complex disorders, it can also affect otherwise healthy children. Medical treatment strategies are frequently required when adenotonsillectomy is not indicated in children with OSA or if OSA is persistent following adenotonsillectomy. Positive airway pressure treatment is a very effective modality for persistent OSA in childhood; however, adherence rates are low. The aim of this review article is to summarize medical treatment options for OSA in children.

摘要

阻塞性睡眠呼吸暂停(OSA)的特征是上呼吸道反复出现完全或部分阻塞。2至8岁儿童的患病率为1%-4%,且由于儿童肥胖率上升而呈上升趋势。虽然腺样体扁桃体切除术后持续性OSA通常与肥胖及潜在的复杂疾病有关,但它也可能影响原本健康的儿童。当OSA患儿不适合进行腺样体扁桃体切除术或腺样体扁桃体切除术后仍存在OSA时,通常需要采取药物治疗策略。气道正压通气治疗是儿童持续性OSA的一种非常有效的治疗方式;然而,依从率较低。这篇综述文章的目的是总结儿童OSA的药物治疗选择。

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What's New in Pediatric Obstructive Sleep Apnea?小儿阻塞性睡眠呼吸暂停有哪些新进展?
Sleep Med Clin. 2023 Jun;18(2):173-181. doi: 10.1016/j.jsmc.2023.02.002. Epub 2023 Mar 9.
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Phentermine/Topiramate: Pediatric First Approval.苯丁胺/托吡酯:儿科首次批准。
Paediatr Drugs. 2022 Nov;24(6):715-720. doi: 10.1007/s40272-022-00532-z.

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