Division of Respiratory Medicine, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada.
Division of Pulmonary and Sleep Medicine, Seattle Children's Hospital, Seattle, WA, USA; Department of Pediatrics, University of Washington, Seattle, WA, USA.
Lancet Respir Med. 2023 Mar;11(3):283-296. doi: 10.1016/S2213-2600(22)00262-4. Epub 2022 Sep 23.
Unresolved obstructive sleep apnoea (OSA) after an adenotonsillectomy, henceforth referred to as persistent OSA, is increasingly recognised in children (2-18 years). Although associated with obesity, underlying medical complexity, and craniofacial disorders, persistent OSA also occurs in otherwise healthy children. Inadequate treatment of persistent OSA can lead to long-term adverse health outcomes beyond childhood. Positive airway pressure, used as a one-size-fits-all primary management strategy for persistent childhood OSA, is highly efficacious but has unacceptably low adherence rates. A pressing need exists for a broader, more effective management approach for persistent OSA in children. In this Personal View, we discuss the use and the need for evaluation of current and novel therapeutics, the role of shared decision-making models that consider patient preferences, and the importance of considering the social determinants of health in research and clinical practice. A multipronged, comprehensive approach to persistent OSA might achieve better clinical outcomes in childhood and promote health equity for all children.
腺扁桃体切除术(adenotonsillectomy)后未解决的阻塞性睡眠呼吸暂停(obstructive sleep apnoea,OSA),以下简称持续性 OSA,在儿童(2-18 岁)中越来越受到关注。尽管持续性 OSA 与肥胖、潜在的医学复杂性和颅面畸形有关,但在其他方面健康的儿童中也会发生。持续性 OSA 治疗不足可能会导致儿童期后长期的不良健康后果。持续儿童 OSA 的单一管理策略即气道正压通气(positive airway pressure),虽然疗效显著,但患者的依从性却低得令人无法接受。因此,迫切需要一种更广泛、更有效的持续性 OSA 管理方法。在本个人观点中,我们讨论了当前和新型治疗方法的应用和评估、考虑患者偏好的共享决策模型的作用,以及在研究和临床实践中考虑健康的社会决定因素的重要性。针对持续性 OSA 的多管齐下的综合方法可能会改善儿童的临床结局,并促进所有儿童的健康公平。