Huber Florian A, Schmidt Cynthia S, Alkadhi Hatem
Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, University of Zurich, Raemistrasse 100, 8091 Zurich, Switzerland.
Diagnostics (Basel). 2023 Aug 7;13(15):2616. doi: 10.3390/diagnostics13152616.
Spondylolysis is underdiagnosed and often missed in non-musculoskeletal abdominal CT imaging. Our aim was to assess the inter-reader agreement and diagnostic performance of a novel "Darth Vader sign" for the detection of spondylolysis in routine axial images. We performed a retrospective search in the institutional report archives through keyword strings for lumbar spondylolysis and spondylolisthesis. Abdominal CTs from 53 spondylolysis cases (41% female) and from controls ( = 6) without spine abnormalities were identified. A total of 139 single axial slices covering the lumbar spine (86 normal images, 40 with spondylolysis, 13 with degenerative spondylolisthesis without spondylolysis) were exported. Two radiology residents rated all images for the presence or absence of the "Darth Vader sign". The diagnostic accuracy for both readers, as well as the inter-reader agreement, was calculated. The "Darth Vader sign" showed an inter-reader agreement of 0.77. Using the "Darth Vader sign", spondylolysis was detected with a sensitivity and specificity of 65.0-88.2% and 96.2-99.0%, respectively. The "Darth Vader sign" shows excellent diagnostic performance at a substantial inter-reader agreement for the detection of spondylolysis. Using the "Darth Vader sign" in the CT reading routine may be an easy yet effective tool to improve the detection rate of spondylolysis in non-musculoskeletal cases and hence improve patient care.
腰椎峡部裂在非肌肉骨骼系统腹部CT成像中常被漏诊。我们的目的是评估一种新型“达斯·维达征”在常规轴向图像中检测腰椎峡部裂的阅片者间一致性和诊断性能。我们通过关键词组在机构报告档案中进行回顾性检索,查找腰椎峡部裂和腰椎滑脱。确定了53例腰椎峡部裂病例(41%为女性)以及6例无脊柱异常的对照者的腹部CT。共导出139张覆盖腰椎的单轴位图像(86张正常图像、40张有峡部裂的图像、13张有退行性腰椎滑脱但无峡部裂的图像)。两名放射科住院医师对所有图像进行“达斯·维达征”有无的评估。计算两位阅片者的诊断准确性以及阅片者间一致性。“达斯·维达征”的阅片者间一致性为0.77。使用“达斯·维达征”检测腰椎峡部裂的敏感度和特异度分别为65.0% - 88.2%和96.2% - 99.0%。“达斯·维达征”在检测腰椎峡部裂时,阅片者间一致性高,诊断性能良好。在CT阅片常规中使用“达斯·维达征”可能是一种简单而有效的工具,可提高非肌肉骨骼系统病例中腰椎峡部裂的检出率,从而改善患者护理。