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超声检测间隔辅助的富血小板血浆治疗复发性犬耳血肿:病例系列

Platelet- Rich Plasma Treatment Supported by Ultrasound Detection of Septa in Recurrent Canine Aural Hematoma: A Case Series.

作者信息

Palagiano Paola, Graziano Lisa, Scarabello Walter, Berni Priscilla, Andreoli Valentina, Grolli Stefano

机构信息

Clinica Veterinaria Meda, 20821 Meda, Italy.

MYPETCLINIC s.r.l., 20149 Milano, Italy.

出版信息

Animals (Basel). 2023 Jul 29;13(15):2456. doi: 10.3390/ani13152456.

DOI:10.3390/ani13152456
PMID:37570265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10417061/
Abstract

Aural hematoma is a common pathological condition in veterinary practice with a high incidence rate in dogs. Drainage, corticosteroid injections, and surgical approaches represent the common treatments in these clinical cases. However, surgery leaves visible signs and is usually correlated with recurrence, scars, and deformation of the treated pinna. For this reason, more effective and less invasive methods have been proposed over the years. Platelet-Rich Plasma (PRP) is one of the most promising options due to its pro-regenerative properties and capability to modulate the inflammatory state. The present work reports 12 cases of canine aural hematoma treated with PRP. The PRP treatment was combined with an ultrasound evaluation of the pinna to detect and treat all involved septa. The results show that relatively large volumes (2 mL) of PRP associated with an ultrasound guide are safe and efficacious in the treatment of canine aural hematoma requiring a maximum of two infiltrations, both in acute and chronic conditions. All the patients recovered their normal ear thickness (compared with the controlateral one) without relapses, averaging 38.5 days from their first treatment (10-90 days; SD: 24.7). The key role of PRP combined with a tailored diagnosis process carried out by the veterinarian, which included using an ultrasound system and the proper bandage, suggests that this approach may represent a valid alternative to surgery and corticosteroids.

摘要

耳血肿是兽医临床上一种常见的病理状况,在犬类中发病率较高。引流、注射皮质类固醇和手术方法是这些临床病例的常见治疗手段。然而,手术会留下明显痕迹,且通常与复发、瘢痕以及治疗后耳廓变形有关。因此,多年来人们提出了更有效且侵入性更小的方法。富血小板血浆(PRP)因其促进再生的特性和调节炎症状态的能力,是最有前景的选择之一。本研究报告了12例采用PRP治疗的犬耳血肿病例。PRP治疗结合耳廓超声评估,以检测和治疗所有受累间隔。结果表明,在超声引导下,相对大量(2 mL)的PRP对于治疗犬耳血肿是安全有效的,无论是急性还是慢性病例,最多只需两次注射。所有患者的耳朵厚度恢复正常(与对侧相比),且无复发,首次治疗后平均38.5天恢复(10 - 90天;标准差:24.7)。PRP结合兽医进行的定制诊断过程(包括使用超声系统和合适的包扎)的关键作用表明,这种方法可能是手术和皮质类固醇的有效替代方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00dc/10417061/68dc633b88dc/animals-13-02456-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00dc/10417061/a1c26dc0bb7e/animals-13-02456-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00dc/10417061/68dc633b88dc/animals-13-02456-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00dc/10417061/a1c26dc0bb7e/animals-13-02456-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00dc/10417061/68dc633b88dc/animals-13-02456-g002.jpg

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本文引用的文献

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Sci Rep. 2021 Nov 9;11(1):21670. doi: 10.1038/s41598-021-00352-0.
2
Antibacterial Properties of Canine Platelet-Rich Plasma and Other Non-Transfusional Hemo-Components: An Study.犬富血小板血浆及其他非输血性血液成分的抗菌特性:一项研究
Front Vet Sci. 2021 Oct 4;8:746809. doi: 10.3389/fvets.2021.746809. eCollection 2021.
3
Use of Autologous Leucocyte- and Platelet-Rich Plasma (L-PRP) in the Treatment of Aural Hematoma in Dogs.
自体富白细胞和血小板血浆(L-PRP)在犬耳血肿治疗中的应用
Vet Sci. 2021 Aug 28;8(9):172. doi: 10.3390/vetsci8090172.
4
Platelet-rich plasma: a narrative review.富血小板血浆:一篇叙述性综述。
EFORT Open Rev. 2021 Apr 1;6(4):225-235. doi: 10.1302/2058-5241.6.200017. eCollection 2021 Apr.
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Autologous Platelet-Rich Plasma Enhances the Healing of Large Cutaneous Wounds in Dogs.自体富血小板血浆促进犬大面积皮肤伤口愈合。
Front Vet Sci. 2020 Oct 26;7:575449. doi: 10.3389/fvets.2020.575449. eCollection 2020.
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Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020.富含血小板血浆:2020 年的新性能认识和治疗考虑。
Int J Mol Sci. 2020 Oct 21;21(20):7794. doi: 10.3390/ijms21207794.
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Aural hematoma and it's treatment: A review.耳血肿及其治疗:综述
Can Vet J. 2020 Mar;61(3):313-315.
8
On the nature of canine aural haematoma and its treatment with continuous vacuum drainage.犬耳血肿的本质及其持续负压引流治疗
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