Wang Yanmin, Alexander Michael, Scott Todd, Cox Desiree C T, Wellington Augusta, Chan Mike K S, Wong Michelle B F, Adalsteinsson Orn, Lakey Jonathan R T
California Medical Innovations Institute, 11107 Roselle Street, San Diego, CA 92121, USA.
Department of Surgery, University of California Irvine, Irvine, CA 92868, USA.
Animals (Basel). 2023 Jul 29;13(15):2457. doi: 10.3390/ani13152457.
Stem cell therapy is an attractive treatment for diseases in companion animals that cannot be treated by conventional veterinary medicine practices. The unique properties of stem cells, particularly the ability to differentiate into specific cell types, makes them a focal point in regenerative medicine treatments. Stem cell transplantation, especially using mesenchymal stem cells, has been proposed as a means to treat a wide range of injuries and ailments, resulting in tissue regeneration or repair. This review aims to summarize the veterinary use of stem cells for treating age-related and joint diseases, which are common conditions in pets. While additional research is necessary and certain limitations exist, the potential of stem cell therapy for companion animals is immense.
干细胞疗法是伴侣动物疾病的一种有吸引力的治疗方法,这些疾病无法通过传统兽医学方法治疗。干细胞的独特特性,特别是分化为特定细胞类型的能力,使其成为再生医学治疗的焦点。干细胞移植,尤其是使用间充质干细胞,已被提议作为治疗多种损伤和疾病的手段,从而实现组织再生或修复。本综述旨在总结干细胞在兽医领域用于治疗宠物常见的与年龄相关疾病和关节疾病的应用。虽然还需要更多研究且存在一定局限性,但干细胞疗法对伴侣动物的潜力巨大。