Varkoulis Konstantinos, Savvas Ioannis, Anagnostou Tilemachos, Kazakos George, Pavlidou Kiriaki
Companion Animal Clinic, School of Veterinary Medicine, Aristotle University of Thessaloniki, 546 27 Thessaloniki, Greece.
Animals (Basel). 2023 Aug 1;13(15):2486. doi: 10.3390/ani13152486.
This retrospective cohort study investigated the mortality rate during anaesthesia and possible contributing factors in canine and feline population in an academic institution in Greece. Data on 1187 dogs and 250 cats which underwent general anaesthesia from 1 January 2018 to 31 December 2019 at the Veterinary Faculty of the Aristotle University of Thessaloniki were analysed regarding cardiac arrest and mortality. In dogs, the rate of cardiac arrest was 1.1% and the rate of death was 0.6%. In cats, these rates were 2.8% and 0.8%, respectively. The mortality rate in healthy/mild disease (ASA I-II) dogs was 0.1% and in cats was 0.5%. Sick (ASA III-V) dogs exhibited a death rate of 2.6%, while sick cats had a rate of 2.2%. In dogs, ASA status had a positive association with cardiac arrest and mortality, with sick dogs being 23 times more likely to suffer cardiac arrest and 24.5 times more likely to die than healthy/mild disease ones. Other factors associated with cardiac arrest and mortality were the anaesthetic protocol and the use of inotropes. In cats, premedication and inotropic support were related to cardiac arrest and death. Feline anaesthesia involves higher risk, and requires greater vigilance in peri-anaesthetic management than dogs.
这项回顾性队列研究调查了希腊一所学术机构中犬猫群体麻醉期间的死亡率及可能的影响因素。对2018年1月1日至2019年12月31日在塞萨洛尼基亚里士多德大学兽医学院接受全身麻醉的1187只犬和250只猫的心脏骤停和死亡数据进行了分析。在犬中,心脏骤停发生率为1.1%,死亡率为0.6%。在猫中,这些发生率分别为2.8%和0.8%。健康/轻度疾病(ASA I-II级)犬的死亡率为0.1%,猫为0.5%。患病(ASA III-V级)犬的死亡率为2.6%,而患病猫的死亡率为2.2%。在犬中,ASA状态与心脏骤停和死亡率呈正相关,患病犬发生心脏骤停的可能性是健康/轻度疾病犬的23倍,死亡可能性是其24.5倍。与心脏骤停和死亡率相关的其他因素是麻醉方案和血管活性药物的使用。在猫中,术前用药和血管活性药物支持与心脏骤停和死亡有关。猫麻醉的风险更高,在围麻醉期管理中比犬需要更高的警惕性。