Facultad de Ingeniería y Administración, Universidad Nacional de Colombia, Carrera. 32 Chapinero, Palmira 763533, Colombia.
Grupo de Investigación GAIDA, Departamento de Procesos Industriales, Facultad de Ingeniería Agroindustrial, Pasto 522020, Colombia.
Molecules. 2023 Aug 3;28(15):5864. doi: 10.3390/molecules28155864.
In vitro and in vivo studies have demonstrated the bioactivity of rutin, a dietary flavonol naturally found in several plant species. Despite widespread knowledge of its numerous health benefits, such as anti-inflammatory, antidiabetic, hepatoprotective and cardiovascular effects, industrial use of rutin is still limited due to its low solubility in aqueous media, the characteristic bitter and astringent taste of phenolic compounds and its susceptibility to degradation during processing. To expand its applications and preserve its biological activity, novel encapsulation systems have been developed. This review presents updated research on the extraction sources and methodologies of rutin from fruit and vegetable products commonly found in a regular diet and grown using family farming approaches. Additionally, this review covers quantitative analysis techniques, encapsulation methods utilizing nanoparticles, colloidal and heterodisperse systems, as well as industrial applications of rutin.
体外和体内研究已经证明了芦丁的生物活性，芦丁是一种天然存在于多种植物物种中的膳食类黄酮。尽管人们广泛了解其众多健康益处，如抗炎、抗糖尿病、保肝和心血管作用，但由于其在水介质中的低溶解度、酚类化合物的典型苦味和涩味以及在加工过程中易降解，芦丁的工业用途仍然有限。为了扩大其应用范围并保持其生物活性，已经开发了新型的封装系统。本综述介绍了从常规饮食中常见的水果和蔬菜产品以及采用家庭农业方法种植的水果和蔬菜产品中提取芦丁的最新研究。此外，本综述还涵盖了芦丁的定量分析技术、利用纳米粒子、胶体和多分散体系进行的封装方法以及工业应用。
