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儿童和青少年的三叉自主神经性头痛和神经痛:叙述性综述。

Trigeminal Autonomic Cephalalgias and Neuralgias in Children and Adolescents: a Narrative Review.

机构信息

Division of Child Neurology, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN, USA.

Pediatric Headache Program, Children's Hospital of Philadelphia, Philadelphia, PA, USA.

出版信息

Curr Neurol Neurosci Rep. 2023 Sep;23(9):539-549. doi: 10.1007/s11910-023-01288-w. Epub 2023 Aug 12.

DOI:10.1007/s11910-023-01288-w
PMID:37572226
Abstract

PURPOSE OF REVIEW

To summarize the available literature as well as the authors' experience on trigeminal autonomic cephalalgias (TACs) and cranial neuralgias in children and adolescents.

RECENT FINDINGS

While TACs and cranial neuralgias are rare in children, several recent case series have been published. TACs in children share most of the clinical features of TACs in adults. However, there are many reported cases with clinical features which overlap more than one diagnosis, suggesting that TACs may be less differentiated in youth. Indomethacin-responsive cases of cluster headache and SUNCT/SUNA have been reported in children, whereas in adults indomethacin is usually reserved for paroxysmal hemicrania and hemicrania continua. Neuralgias appear to be rare in children. Clinical features are often similar to adult cases, though clinicians should maintain a high index of suspicion for underlying causes.

摘要

目的综述

总结有关儿童和青少年三叉神经自主神经性头痛(TACs)和颅神经痛的现有文献以及作者的经验。

最新发现

尽管 TACs 和颅神经痛在儿童中较为罕见,但已有数项近期病例系列研究发表。儿童 TACs 具有与成人 TACs 大部分相同的临床特征。然而,有许多报道的病例具有重叠多个诊断的临床特征,提示 TACs 在青少年中可能不太分化。儿童中也有报道对吲哚美辛有反应的丛集性头痛和 SUNCT/SUNA 病例,而在成人中,吲哚美辛通常保留用于阵发性偏头痛和慢性偏头痛。神经痛在儿童中似乎很少见。临床特征通常与成人病例相似,但临床医生应保持对潜在病因的高度警惕。

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Curr Pain Headache Rep. 2025 May 27;29(1):91. doi: 10.1007/s11916-025-01403-1.
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Cluster Headache: Diagnosis, Management, and Treatment in Pediatric Headache.丛集性头痛:儿童头痛的诊断、管理与治疗
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本文引用的文献

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Effects of acupuncture in the treatment of occipital neuralgia: A systematic review and meta-analysis.针灸治疗枕神经痛的疗效:系统评价和荟萃分析。
Medicine (Baltimore). 2022 Dec 2;101(48):e31891. doi: 10.1097/MD.0000000000031891.
2
The spectrum of indomethacin-responsive headaches in children and adolescents.儿童和青少年吲哚美辛反应性头痛的谱。
Cephalalgia. 2022 Jul;42(8):793-797. doi: 10.1177/03331024221076483. Epub 2022 Mar 18.
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Cluster headache epidemiology including pediatric onset, sex, and ICHD criteria: Results from the International Cluster Headache Questionnaire.
丛集性头痛的流行病学,包括儿童发病、性别和 ICHD 标准:国际丛集性头痛问卷的结果。
Headache. 2021 Nov;61(10):1511-1520. doi: 10.1111/head.14237. Epub 2021 Nov 28.
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An Update on the Diagnosis, Treatment, and Management of Occipital Neuralgia.关于枕神经痛的诊断、治疗和管理的最新进展。
J Craniofac Surg. 2022 May 1;33(3):779-783. doi: 10.1097/SCS.0000000000008360. Epub 2021 Nov 9.
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Cranial Neuralgias in Children and Adolescents A review of the literature.儿童和青少年颅神经痛文献综述
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Pediatric-onset trigeminal autonomic cephalalgias: A systematic review and meta-analysis.儿童期起病的三叉自主神经性头痛:系统评价和荟萃分析。
Cephalalgia. 2021 Nov;41(13):1382-1395. doi: 10.1177/03331024211027560. Epub 2021 Aug 18.
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Occipital Neuralgia.枕神经痛。
Curr Pain Headache Rep. 2021 Jul 21;25(9):61. doi: 10.1007/s11916-021-00972-1.
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Trigeminal neuralgia: a practical guide.三叉神经痛:实用指南。
Pract Neurol. 2021 Oct;21(5):392-402. doi: 10.1136/practneurol-2020-002782. Epub 2021 Jun 9.
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Cluster headache in children and adolescents: a systematic review of case reports.儿童和青少年集群性头痛:病例报告的系统评价。
Dev Med Child Neurol. 2021 Oct;63(10):1155-1160. doi: 10.1111/dmcn.14923. Epub 2021 May 14.
10
Long-Term Outcome of Indomethacin Treatment in Pediatric Patients with Paroxysmal Hemicrania-A Case Series.小儿发作性偏侧头痛患者吲哚美辛治疗的长期结果——病例系列
Children (Basel). 2021 Feb 3;8(2):101. doi: 10.3390/children8020101.