Division of Child Neurology, Le Bonheur Children's Hospital, University of Tennessee Health Science Center, Memphis, TN, USA.
Pediatric Headache Program, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Curr Neurol Neurosci Rep. 2023 Sep;23(9):539-549. doi: 10.1007/s11910-023-01288-w. Epub 2023 Aug 12.
To summarize the available literature as well as the authors' experience on trigeminal autonomic cephalalgias (TACs) and cranial neuralgias in children and adolescents.
While TACs and cranial neuralgias are rare in children, several recent case series have been published. TACs in children share most of the clinical features of TACs in adults. However, there are many reported cases with clinical features which overlap more than one diagnosis, suggesting that TACs may be less differentiated in youth. Indomethacin-responsive cases of cluster headache and SUNCT/SUNA have been reported in children, whereas in adults indomethacin is usually reserved for paroxysmal hemicrania and hemicrania continua. Neuralgias appear to be rare in children. Clinical features are often similar to adult cases, though clinicians should maintain a high index of suspicion for underlying causes.
总结有关儿童和青少年三叉神经自主神经性头痛(TACs)和颅神经痛的现有文献以及作者的经验。
尽管 TACs 和颅神经痛在儿童中较为罕见,但已有数项近期病例系列研究发表。儿童 TACs 具有与成人 TACs 大部分相同的临床特征。然而,有许多报道的病例具有重叠多个诊断的临床特征,提示 TACs 在青少年中可能不太分化。儿童中也有报道对吲哚美辛有反应的丛集性头痛和 SUNCT/SUNA 病例,而在成人中,吲哚美辛通常保留用于阵发性偏头痛和慢性偏头痛。神经痛在儿童中似乎很少见。临床特征通常与成人病例相似,但临床医生应保持对潜在病因的高度警惕。