University of Regensburg, Institute for Experimental Psychology, Universitätsstraße 31, 93053 Regensburg, Germany.
University of Regensburg, Institute for Experimental Psychology, Universitätsstraße 31, 93053 Regensburg, Germany.
STAR Protoc. 2023 Sep 15;4(3):102493. doi: 10.1016/j.xpro.2023.102493. Epub 2023 Aug 11.
We present a protocol to conduct functional magnetic resonance spectroscopy (fMRS) in human participants before, during, and after training on a visual task. We describe steps for participant setup, volume-of-interest placement, fMRS measurement, and post-scan tests. We discuss the design, analysis, and interpretation of fMRS experiments. This protocol can be adapted to investigate the dynamics of chief excitatory and inhibitory neurotransmitters (glutamate and γ-aminobutyric acid, GABA, respectively) while participants perform or learn perceptual, motor, or cognitive tasks. For complete details on the use and execution of this protocol, please refer to Frank et al. (2022)..
我们提出了一个方案，在人类参与者进行视觉任务的训练之前、期间和之后进行功能磁共振波谱（fMRS）测量。我们描述了参与者设置、感兴趣区放置、fMRS 测量以及扫描后测试的步骤。我们讨论了 fMRS 实验的设计、分析和解释。本方案可以进行修改，以研究主要兴奋性和抑制性神经递质（谷氨酸和γ-氨基丁酸，分别）在参与者执行或学习感知、运动或认知任务时的动态变化。有关本方案使用和执行的完整详细信息，请参考 Frank 等人（2022 年）。
