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COVID-19 相关急性呼吸窘迫综合征患者行俯卧位治疗的压力性损伤发生率及其影响。

Pressure injury incidence and impact on patients treated with prone positioning for COVID-19 ARDS.

机构信息

Department of Intensive Care, Dubai Hospital, Dubai, UAE.

Dubai Hospital, Medical Intensive Care Unit, Dubai, UAE.

出版信息

J Wound Care. 2023 Aug 2;32(8):500-506. doi: 10.12968/jowc.2023.32.8.500.

Abstract

OBJECTIVE

To determine the incidence of pressure injuries (PIs) and their impact on clinical outcomes in patients treated with prone positioning for COVID-19 acute respiratory distress syndrome (ARDS).

METHOD

All patients with COVID-19 ARDS who were treated with prone positioning were categorised as cases and those who were not treated with prone positioning were categorised as controls. Demographics, clinical data and confounding variables affecting outcomes were recorded. Outcome variables of mortality and length of stay in intensive care units (ICUs) for both groups were recorded. Both groups' incidence of PIs were recorded and compared using statistical tests. Fisher's exact test was used for categorical variables, and Mann-Whitney U test was used for continuous variables.

RESULTS

The sample included 212 patients, treated with prone position (n=104) and without prone treatment (n=108). The incidence of PIs was n=75 (35.4%). PIs were significantly higher in patients in the prone position (n=51, 49%) compared with patients who were not (n=24, 22%); p=0.001. Patients in the prone position were found to have lower APACHE-2 scores, longer stays on the ventilator, ICU and in the hospital.

CONCLUSION

PIs are more prevalent in patients in the prone position and it adversely impacts clinical outcomes; it prolongs the length of stay on the ventilator, in the ICU and in the hospital.

摘要

目的

确定 COVID-19 急性呼吸窘迫综合征(ARDS)患者采用俯卧位治疗后压力性损伤(PI)的发生率及其对临床结局的影响。

方法

将所有接受俯卧位治疗的 COVID-19 ARDS 患者分为病例组,未接受俯卧位治疗的患者分为对照组。记录患者的人口统计学、临床数据和影响结局的混杂变量。记录两组患者的死亡率和重症监护病房(ICU)住院时间等结局变量。使用统计学检验比较两组患者 PI 的发生率。对于分类变量,使用 Fisher 确切检验;对于连续变量,使用 Mann-Whitney U 检验。

结果

本研究纳入了 212 例患者,其中 104 例接受俯卧位治疗,108 例未接受俯卧位治疗。PI 的发生率为 n=75(35.4%)。与未接受俯卧位治疗的患者(n=24,22%)相比,接受俯卧位治疗的患者(n=51,49%)PI 发生率更高,p=0.001。接受俯卧位治疗的患者的急性生理与慢性健康评分-2 (APACHE-2)评分更低,呼吸机使用时间、ICU 住院时间和总住院时间更长。

结论

接受俯卧位治疗的患者 PI 更常见,且对临床结局产生不利影响;它延长了呼吸机使用时间、ICU 住院时间和总住院时间。

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