Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, South Africa.
Department of Paraclinical Sciences, Faculty of Veterinary Science, University of Pretoria, South Africa.
Environ Toxicol Pharmacol. 2023 Sep;102:104244. doi: 10.1016/j.etap.2023.104244. Epub 2023 Aug 10.
Cape Vultures (Gyps coprotheres) are a vulnerable Old-World Vulture species in southern Africa. Of the numerous threats to their survival, malicious and accidental poisonings remain a major concern. Despite the dangers of poisonings little is however known about the more insidious effects of toxins on egg survival, despite the species known to have a long generational length. For this study, an extensive literature review focusing on veterinary pharmaceuticals was undertaken. Literature for vultures was scarce, with most studies focusing on the domestic chicken. Using information for domestic chickens, the risk was characterised from likely vulture exposure to production animal carcasses with residues of said drugs. From this various antibiotics, medetomidine and albendazole were identified with embryotoxic or teratogenic effects. We suggest that these drugs be tested to elucidate their dose-response relationship and/or mitigation measures to minimise vulture exposure.
海角秃鹫（Gyps coprotheres）是南非一种脆弱的旧大陆秃鹫物种。在对它们生存造成的众多威胁中，恶意和意外中毒仍然是一个主要关注点。尽管中毒的危险很大，但对于毒素对卵存活的更隐蔽影响却知之甚少，尽管该物种已知具有较长的世代长度。在这项研究中，我们进行了一项广泛的文献综述，重点关注兽医药品。关于秃鹫的文献很少，大多数研究都集中在家养鸡上。利用关于家养鸡的信息，从可能接触到含有这些药物的生产动物尸体的秃鹫的角度，评估了风险。从这些药物中，我们确定了各种具有胚胎毒性或致畸作用的抗生素、美托咪定和阿苯达唑。我们建议对这些药物进行测试，以阐明它们的剂量反应关系和/或减轻措施，以尽量减少秃鹫接触。
