Chen Luyan, Nie Zhenyu, Zhao Yu, Bao Beiyan
Health Science center, Ningbo University, Ningbo, China.
Department of Nephrology, Ningbo Yinzhou No.2 Hospital (Ningbo Urology and Nephrology Hospital), Ningbo, China.
Indian J Med Microbiol. 2023 Sep-Oct;45:100410. doi: 10.1016/j.ijmmb.2023.100410. Epub 2023 Jul 3.
We report a patient diagnosed with peritonitis due to a rare infection of Ureaplasma parvum after receiving peritoneal dialysis for two years. This microorganism rarely causes peritoneal dialysis-associated peritonitis (PDAP). This is the first case of PDAP caused by Ureaplasma parvum. In the present case, the pathogen was identified through next-generation sequencing of PD fluid samples. The patient was treated with intraperitoneal (IP) levofloxacin combined with vancomycin and oral clarithromycin which effectively improved her symptoms. This case creates awareness that Ureaplasma parvum can cause PDAP and can be diagnosed using next-generation sequencing(NGS).
我们报告了一名患者，该患者在接受两年腹膜透析后，因罕见的微小脲原体感染而被诊断为腹膜炎。这种微生物很少引起腹膜透析相关腹膜炎（PDAP）。这是首例由微小脲原体引起的PDAP病例。在本病例中，通过对腹膜透析液样本进行二代测序鉴定出病原体。该患者接受了腹腔内（IP）左氧氟沙星联合万古霉素以及口服克拉霉素治疗，症状得到有效改善。该病例提醒人们，微小脲原体可导致PDAP，且可通过二代测序（NGS）进行诊断。
