Ye Jiajia, Sun Jing, Chen Dan, Cao Huanhuan, Lv Yi, Ye Chen, Wang Yumei, Jiang Huajun
Department of Nephrology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Department of Nephrology, The Affiliated Hospital of Hubei Provincial Government, Wuhan, China.
Kidney Dis (Basel). 2024 Dec 2;11(1):25-37. doi: 10.1159/000542870. eCollection 2025 Jan-Dec.
Peritonitis is a common and serious complication of peritoneal dialysis that results in considerable morbidity, mortality, and increased healthcare costs. A positive culture-based microorganism test is one of the main criteria for the diagnosis of peritonitis. However, the rates of positive bacterial culture remain quite low.
Peritonitis is a frequently encountered and consequential complication of peritoneal dialysis that poses a significant clinical burden in terms of morbidity, mortality, and healthcare expenditure. The reliance on culture-positive microbiological tests as a cornerstone of peritonitis diagnosis often results in a relatively low rate of positive results.
This article aimed to present a comprehensive synthesis and critical analysis of the most recent diagnostic modalities used to identify peritonitis-associated pathogens in peritoneal dialysis. Emphasis was placed on both direct diagnostic tools for pathogen identification and rapid detection methodologies that facilitate expedited pathogen diagnosis in peritonitis.
腹膜炎是腹膜透析常见且严重的并发症，会导致相当高的发病率、死亡率，并增加医疗成本。基于培养的微生物检测呈阳性是腹膜炎诊断的主要标准之一。然而，细菌培养阳性率仍然相当低。
腹膜炎是腹膜透析中经常遇到且后果严重的并发症，在发病率、死亡率和医疗支出方面构成了重大的临床负担。依赖培养阳性的微生物检测作为腹膜炎诊断的基石往往导致阳性结果率相对较低。
本文旨在对用于识别腹膜透析中与腹膜炎相关病原体的最新诊断方法进行全面综述和批判性分析。重点关注病原体识别的直接诊断工具以及有助于在腹膜炎中快速诊断病原体的快速检测方法。
