Cermakova Pavla, Csajbók Zsófia
Second Faculty of Medicine, Charles University Prague, Czechia; National Institute of Mental Health, Klecany, Czechia.
Faculty of Humanities, Charles University Prague, Czechia.
J Affect Disord. 2023 Nov 1;340:456-461. doi: 10.1016/j.jad.2023.08.056. Epub 2023 Aug 16.
We aimed to investigate the association of household crowding in childhood with trajectories of depressive symptoms in middle-aged and older adults.
We studied 47,010 participants (56 % women, 63 years at baseline) from SHARE. Using multinomial logistic regression, we estimated odds ratio (OR) with 95 % confidence interval (CI) for the association of household crowding in childhood (number of household members/number of rooms at the age of 10) with trajectories of depressive symptoms (EURO-D scale), which were generated with growth mixture modeling. We adjusted for resources in childhood, sociodemographic and health-related characteristics in mid-life and older age and tested effect modification by sex.
We identified four trajectories of depressive symptoms: constantly low (n = 33,969), decreasing (n = 5595), increasing (n = 5574) and constantly high (n = 1872). When compared to the those with constantly low depressive symptoms and adjusting for all covariates, household crowding in childhood was associated with greater odds of constantly high (OR 1.12; 95 % CI 1.08-1.17), decreasing (OR 1.11; 95 % CI 1.07-1.15) and increasing (OR 1.09; 95 % CI 1.06-1.13) depressive symptoms. The associations were stronger in women than in men.
Prevention of household crowding in childhood may ameliorate the development of constant as well as transient depressive symptoms during ageing. The effect can be stronger in women than in men.
我们旨在研究童年时期家庭拥挤状况与中老年人群抑郁症状轨迹之间的关联。
我们对来自“健康、退休和老龄化纵向研究”(SHARE)的47010名参与者(56%为女性,基线年龄63岁)进行了研究。使用多项逻辑回归,我们估计了童年时期家庭拥挤状况(10岁时家庭成员数量/房间数量)与抑郁症状轨迹(欧洲抑郁量表)之间关联的比值比(OR)及95%置信区间(CI),抑郁症状轨迹通过生长混合模型生成。我们对童年时期的资源、中年及老年时期的社会人口学和健康相关特征进行了调整,并检验了性别对效应的修饰作用。
我们识别出四条抑郁症状轨迹:持续低水平(n = 33969)、下降(n = 5595)、上升(n = 5574)和持续高水平(n = 1872)。与抑郁症状持续低水平的人群相比,并在对所有协变量进行调整后,童年时期家庭拥挤与抑郁症状持续高水平(OR 1.12;95% CI 1.08 - 1.17)、下降(OR 1.11;95% CI 1.07 - 1.15)及上升(OR 1.09;95% CI 1.06 - 1.13)的更高几率相关。女性中的关联比男性更强。
预防童年时期的家庭拥挤可能会改善衰老过程中持续及短暂抑郁症状的发展。女性的效果可能比男性更强。