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The analgesic effect of rescue administration of intravenous acetaminophen in cancer patients may be associated with sex and opioid dose, and the effect would appear to patients administered under 45 mg/day opioid (oral morphine equivalents).癌症患者静脉注射对乙酰氨基酚进行解救给药的镇痛效果可能与性别和阿片类药物剂量有关,且该效果似乎在每日阿片类药物剂量低于45毫克(口服吗啡等效剂量)的患者中出现。
Pharmazie. 2018 Mar 5;73(3):161-164. doi: 10.1691/ph.2018.7878.
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[An appropriate opioid rotation method for treatment of cancer pain--nationwide usage survey of opioid analgesics].[一种用于治疗癌痛的合适阿片类药物轮换方法——阿片类镇痛药全国使用情况调查]
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Jpn J Clin Oncol. 2015 Feb;45(2):189-96. doi: 10.1093/jjco/hyu182. Epub 2014 Nov 6.
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本文引用的文献

1
CDC Clinical Practice Guideline for Prescribing Opioids for Pain - United States, 2022.美国疾病预防控制中心 2022 年《疼痛阿片类药物处方临床实践指南》。
MMWR Recomm Rep. 2022 Nov 4;71(3):1-95. doi: 10.15585/mmwr.rr7103a1.
2
Misappropriation of the 1986 WHO analgesic ladder: the pitfalls of labelling opioids as weak or strong.滥用 1986 年世卫组织阿片类药物镇痛阶梯:将阿片类药物标记为弱或强的陷阱。
Br J Anaesth. 2022 Aug;129(2):137-142. doi: 10.1016/j.bja.2022.03.004. Epub 2022 Apr 6.
3
Morphine alkaloids: History, biology, and synthesis.吗啡生物碱:历史、生物学与合成。
Alkaloids Chem Biol. 2021;86:145-342. doi: 10.1016/bs.alkal.2021.04.001. Epub 2021 Sep 21.
4
Mu Opioid Receptor Heterodimers Emerge as Novel Therapeutic Targets: Recent Progress and Future Perspective.μ阿片受体异二聚体成为新型治疗靶点:最新进展与未来展望
Front Pharmacol. 2020 Jul 15;11:1078. doi: 10.3389/fphar.2020.01078. eCollection 2020.
5
Basic Opioid Pharmacology - An Update.基础阿片类药物药理学——最新进展
Br J Pain. 2020 May;14(2):115-121. doi: 10.1177/2049463720911986. Epub 2020 Mar 20.
6
Oxycodone versus morphine for cancer pain titration: A systematic review and pharmacoeconomic evaluation.羟考酮与吗啡治疗癌痛滴定:系统评价和药物经济学评价。
PLoS One. 2020 Apr 17;15(4):e0231763. doi: 10.1371/journal.pone.0231763. eCollection 2020.
7
Hot topics in opioid pharmacology: mixed and biased opioids.阿片类药物药理学的热点问题:混合和偏倚阿片类药物。
Br J Anaesth. 2019 Jun;122(6):e136-e145. doi: 10.1016/j.bja.2019.03.006. Epub 2019 Apr 19.
8
Protocol for evaluating the nationwide implementation of the VA Stratification Tool for Opioid Risk Management (STORM).评估 VA 分层工具(STORM)在全国范围内实施的方案。
Implement Sci. 2019 Jan 18;14(1):5. doi: 10.1186/s13012-019-0852-z.
9
Patterns of Immediate-Release and Extended-Release Opioid Analgesic Use in the Management of Chronic Pain, 2003-2014.2003-2014 年慢性疼痛管理中美托咪定即时释放和缓释剂型的使用模式。
JAMA Netw Open. 2018 Jun 1;1(2):e180216. doi: 10.1001/jamanetworkopen.2018.0216.
10
Untangling the complexity of opioid receptor function.解析阿片受体功能的复杂性。
Neuropsychopharmacology. 2018 Dec;43(13):2514-2520. doi: 10.1038/s41386-018-0225-3. Epub 2018 Sep 24.

Opioid administration and rescue dose: exploring the effects of opioid combinations.

作者信息

Kraychete Durval C, Schmidt André P, Souza Anna Karla N, de Barros Guilherme A M

机构信息

Universidade Federal da Bahia (UFBA), Departamento de Anestesiologia e Cirurgia, Salvador, BA, Brasil.

Hospital de Clínicas de Porto Alegre (HCPA), Serviço de Anestesia e Medicina Perioperatória, Porto Alegre, RS, Brasil; Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Santa Casa de Porto Alegre, Serviço de Anestesia, Porto Alegre, RS, Brasil; Hospital Nossa Senhora da Conceição, Serviço de Anestesia, Porto Alegre, RS, Brasil; Universidade Federal do Rio Grande do Sul (UFRGS), Faculdade de Medicina, Programa de Pós-graduação em Ciências Pneumológicas, Porto Alegre, RS, Brasil; Universidade de São Paulo (FMUSP), Faculdade de Medicina, Programa de Pós-Graduação em Anestesiologia, Ciências Cirúrgicas e Medicina Perioperatória, São Paulo, SP, Brasil.

出版信息

Braz J Anesthesiol. 2023 Nov-Dec;73(6):707-710. doi: 10.1016/j.bjane.2023.08.002. Epub 2023 Aug 12.

DOI:10.1016/j.bjane.2023.08.002
PMID:37574112
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10625154/
Abstract
摘要