Wu J, Tang Y Y, Jiang S, Duan Y R, Mu Z H, Wang J, Wang S X, Zhao Y J
School of Public Health, Zhengzhou University, Zhengzhou 450051, China.
Institude for Hospital Management of Henan Province, Zhengzhou 450052, China Operation Management Department, The First Affiliation Hospital of Zhengzhou University, Zhengzhou 450052, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2023 Aug 6;57(8):1135-1140. doi: 10.3760/cma.j.cn112150-20230103-00005.
To analyze the mortality trend and characteristics of chronic obstructive pulmonary disease (COPD) among residents in China from 2004 to 2020. From the area, gender, region, and age dimensions, the Joinpoint regression model was used to analyze the trend of COPD mortality rate from 2004 to 2020, extracted from the China Death Surveillance Dataset. From 2004 to 2020, the mortality rate and age-adjusted mortality rate of COPD showed a downward trend (AAPC=-3.68%, <0.001; AAPC=-7.27%, <0.001), which were consistent with urban and rural subpopulations (mortality rate: AAPC=-3.62%, =0.009, AAPC=-3.23%, =0.014; age-adjusted mortality rate: AAPC=-7.26%, <0.001, AAPC=-6.78%, <0.001). The mortality rate of COPD in rural was higher than that of urban subpopulations (<0.001). Also, the mortality rate and age-adjusted mortality rate of COPD showed a downward trend in males and females (mortality rate: AAPC=-3.00%, <0.001, AAPC=-4.37%, <0.001; age-adjusted mortality rate: AAPC=-6.73%, <0.001, AAPC=-8.11%, <0.001), and the COPD mortality rate for male was generally higher than female (<0.001). Meanwhile, the mortality rate of COPD in eastern, central and western regions also showed a downward trend (AAPC=-3.87%, <0.001; AAPC=-3.12%, <0.001; AAPC=-1.37%, =0.001), and western regions were significantly higher than that in central (<0.001) and eastern (<0.001) regions. The mortality rate of COPD in the age group of Chinese people showed a downward trend in<45, 45-59, and≥60 years groups (AAPC=-9.48%, <0.001; AAPC=-9.03%, <0.001; AAPC=-5.91%, <0.001). Among them,≥60 years groups was significantly higher than that in<45 (<0.001) and 45-59 (<0.001) years groups, and the decline rate was slowest. In China, the mortality rate of COPD decreases from 2004 to 2020, and more efforts are needed to reduce COPD mortality, especially in western regions, rural populations, males and the elderly.
分析2004年至2020年中国居民慢性阻塞性肺疾病（COPD）的死亡率趋势及特征。从地区、性别、区域和年龄维度，采用Joinpoint回归模型分析2004年至2020年中国死亡监测数据集提取的COPD死亡率趋势。2004年至2020年，COPD死亡率和年龄调整死亡率呈下降趋势（年度百分比变化率=-3.68%，<0.001；年度百分比变化率=-7.27%，<0.001），城乡亚人群情况一致（死亡率：年度百分比变化率=-3.62%，=0.009，年度百分比变化率=-3.23%，=0.014；年龄调整死亡率：年度百分比变化率=-7.26%，<0.001，年度百分比变化率=-6.78%，<0.001）。农村地区COPD死亡率高于城市亚人群（<0.001）。此外，男性和女性的COPD死亡率和年龄调整死亡率均呈下降趋势（死亡率：年度百分比变化率=-3.00%，<0.001，年度百分比变化率=-4.37%，<0.001；年龄调整死亡率：年度百分比变化率=-6.73%，<0.001，年度百分比变化率=-8.11%，<0.001），男性COPD死亡率总体高于女性（<0.001）。同时，东部、中部和西部地区的COPD死亡率也呈下降趋势（年度百分比变化率=-3.87%，<0.001；年度百分比变化率=-3.12%，<0.001；年度百分比变化率=-1.37%，=0.001），西部地区显著高于中部（<0.001）和东部（<0.001）地区。中国人<45岁、45 - 59岁和≥60岁年龄组的COPD死亡率呈下降趋势（年度百分比变化率=-9.48%，<0.001；年度百分比变化率=-9.03%，<0.001；年度百分比变化率=-5.91%，<0.001）。其中，≥60岁年龄组显著高于<45岁（<0.001）和45 - 59岁（<0.001）年龄组，且下降速度最慢。在中国，2004年至2020年COPD死亡率下降，仍需进一步努力降低COPD死亡率，尤其是在西部地区、农村人口、男性和老年人中。
