Karamouzian Mohammad, Rafat Bijan, Kolla Gillian, Urbanoski Karen, Atkinson Kate, Bardwell Geoff, Bonn Matthew, Touesnard Natasha, Henderson Nancy, Bowles Jeanette, Boyd Jade, Brunelle Caroline, Eeuwes Jolene, Fikowski Jill, Gomes Tara, Guta Adrian, Hyshka Elaine, Ivsins Andrew, Kennedy Mary Clare, Laurence Gab, Martignetti Lucas, Nafeh Frishta, Salters Kate, Tu David, Strike Carol, Pauly Bernadette, Werb Dan
Centre on Drug Policy Evaluation, MAP Centre for Urban Health Solutions, St. Michael's Hospital, Toronto, ON, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Centre on Drug Policy Evaluation, MAP Centre for Urban Health Solutions, St. Michael's Hospital, Toronto, ON, Canada.
Int J Drug Policy. 2023 Oct;120:104157. doi: 10.1016/j.drugpo.2023.104157. Epub 2023 Aug 11.
Canada is experiencing an unprecedented drug toxicity crisis driven by a highly toxic unregulated drug supply contaminated with fentanyl, benzodiazepine, and other drugs. Safer supply pilot programs provide prescribed doses of pharmaceutical alternatives to individuals accessing the unregulated drug supply and have been implemented to prevent overdose and reduce related harms. Given the recent emergence of these pilot programs and the paucity of data on implementation challenges, we sought to document challenges in their initial implementation phase.
We obtained organizational progress reports from Health Canada, submitted between 2020 and 2022 by 11 pilot programs located in British Columbia, Ontario, and New Brunswick. We analyzed the data using deductive and inductive approaches via thematic analysis. Analyses were informed by the consolidated framework for implementation research.
We obtained 45 progress reports from 11 pilot programs. Six centres were based in British Columbia, four in Ontario, and one in New Brunswick. Four overarching themes were identified regarding the challenges faced during the establishment and implementation of pilot programs: i) Organizational features (e.g., physical space constraints, staff shortages); ii) Outer contexts (e.g., limited operational funds and resources, structural inequities to access, public perceptions); iii) Intervention characteristics (e.g., clients' unmet medication needs); and iv) Implementation process (e.g., pandemic-related challenges, overly medicalized and high-barrier safer supply models).
Safer supply pilot programs in Canada face multiple inner and outer implementation challenges. Given the potential role of safer supply programs in addressing the drug toxicity crisis in Canada and the possibility of future scale-up, services should be well-supported during their implementation phases. Refining service provision within safer supply programs based on the feedback and experiences of clients and program administrators is warranted, along with efforts to ensure that appropriate medications are available to meet the clients' needs.
加拿大正经历一场前所未有的药物中毒危机,其原因是受芬太尼、苯二氮卓类药物及其他药物污染的高毒性无管制药物供应。更安全供应试点项目为使用无管制药物供应的个人提供规定剂量的药品替代品,已实施该项目以预防过量用药并减少相关危害。鉴于这些试点项目近期才出现且关于实施挑战的数据匮乏,我们试图记录其初始实施阶段的挑战。
我们获取了加拿大卫生部的组织进展报告,这些报告由位于不列颠哥伦比亚省、安大略省和新不伦瑞克省的11个试点项目在2020年至2022年期间提交。我们通过主题分析,采用演绎和归纳方法对数据进行了分析。分析以实施研究的综合框架为依据。
我们从11个试点项目中获得了45份进展报告。6个中心位于不列颠哥伦比亚省,4个在安大略省,1个在新不伦瑞克省。确定了关于试点项目设立和实施过程中面临的挑战的四个总体主题:i)组织特征(如物理空间限制、人员短缺);ii)外部环境(如运营资金和资源有限、获取方面的结构性不平等、公众认知);iii)干预特征(如客户未满足的用药需求);以及iv)实施过程(如与大流行相关的挑战、过度医疗化和高门槛的更安全供应模式)。
加拿大更安全供应试点项目面临诸多内部和外部实施挑战。鉴于更安全供应项目在应对加拿大药物中毒危机方面的潜在作用以及未来扩大规模的可能性,应在其实施阶段为这些服务提供充分支持。有必要根据客户和项目管理人员的反馈及经验,优化更安全供应项目中的服务提供,同时努力确保有合适的药物可满足客户需求。