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保险状态对高血糖危象患者住院死亡率的影响:一项倾向评分匹配分析。

The impact of insurance status on in-hospital mortality in patients with hyperglycaemic crisis: A propensity score matching analysis.

作者信息

Chen Zhen, Zhao Xu, He Rui, Li Hong, Fu Shimin, Zhang Kebiao, Gu Manping, Zhou Sumei

机构信息

Department of Emergency, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

出版信息

J Eval Clin Pract. 2023 Dec;29(8):1395-1401. doi: 10.1111/jep.13921. Epub 2023 Aug 21.

Abstract

AIM

This study was designed to determine the associations between insurance status and clinical outcomes among patients with hyperglycaemic crisis.

METHODS

Overall, 1668 patients with hyperglycaemic crisis were recruited from the Chongqing Medical University Medical Data Science Academy's big data platform. In-hospital mortality, length of stay and complications (i.e., hypoglycaemia, hypokalemia, pulmonary infection, multiple systemic organ failure, acute kidney injury and deep venous thrombosis) were assessed. Propensity score matching analysis was used to reduce the confounding bias, and univariate and multivariate logistic regression were used to estimate the effect of insurance status on mortality in patients with hyperglycaemic crisis.

RESULTS

After matching one uninsured patient to two insured patients with a calliper of 0.02, the uninsured group suffered a higher burden of in-hospital mortality than the insured group (16.9% vs. 9.8%); the insured status (odds ratio = 0.216, 95% confidence interval = 0.079-0.587) was a potential protect factor for in-hospital mortality of patients with hyperglycaemic crisis in the multivariate logistic regression analysis.

CONCLUSIONS

Insurance status is associated with the outcomes of hospitalisation for hyperglycaemic crisis; uninsured patients with hyperglycaemic crisis face a higher risk of mortality in China.

摘要

目的

本研究旨在确定高血糖危象患者的保险状况与临床结局之间的关联。

方法

总体而言,从重庆医科大学医学数据科学学院的大数据平台招募了1668例高血糖危象患者。评估了住院死亡率、住院时间和并发症(即低血糖、低钾血症、肺部感染、多系统器官衰竭、急性肾损伤和深静脉血栓形成)。采用倾向评分匹配分析以减少混杂偏倚,并使用单因素和多因素逻辑回归来估计保险状况对高血糖危象患者死亡率的影响。

结果

在将一名未参保患者与两名参保患者以0.02的卡尺进行匹配后,未参保组的住院死亡负担高于参保组(16.9%对9.8%);在多因素逻辑回归分析中,参保状态(比值比=0.216,95%置信区间=0.079-0.587)是高血糖危象患者住院死亡的潜在保护因素。

结论

保险状况与高血糖危象的住院结局相关;在中国,未参保的高血糖危象患者面临更高的死亡风险。

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