寡转移前列腺癌——过去十年概述
Oligometastatic carcinoma prostate - An overview of the last decade.
作者信息
Shah Milap J, Sharma Aditya Prakash, Hameed B M Zeeshan, Jain Ravi, Patil Abhijit, Karthickeyan Naganathan, Singh Abhishek
机构信息
Aarogyam Specialty Hospital, Ahmedabad, India.
Department of Urology, PGIMER, Chandigarh, India.
出版信息
Indian J Urol. 2023 Jul-Sep;39(3):195-201. doi: 10.4103/iju.iju_60_23. Epub 2023 Jun 30.
INTRODUCTION
Oligometastatic prostate cancer (OMPC) has gained profound interest lately due to its different tumor biology and our ability to use multimodality therapy for cure or prolonged survival. Selecting the appropriate patient for treatment has become the aim of treating urologists, medical oncologists, and radiation oncologists. Through this review, we try to highlight the management of OMPC in light of recent literature.
METHODS
Literature search was performed on Pubmed, Scopus and Embase using keywords "Oligometastatic", " Prostate Cancer" using operators such as "And" & "Or". Relevant articles were screened and all the latest articles on this emerging entity were included in this review.
RESULTS
All trials relevant to oligometastatic prostate cancer defining the role of surgery, radiotherapy and systemic therapy were included and appropriate inferences were drawn. Relevant studies were compiled in tabular form for this article.
CONCLUSION
The current standard of care of management for OMPC remains systemic therapy on the lines of hormone-sensitive metastatic prostate cancer. The evolving role of surgery, and radiotherapy along with systemic therapy is highlighted in this article.
引言
寡转移前列腺癌（OMPC）近来引起了广泛关注，因其具有不同的肿瘤生物学特性，且我们有能力采用多模态疗法实现治愈或延长生存期。选择合适的患者进行治疗已成为泌尿外科医生、医学肿瘤学家和放射肿瘤学家的治疗目标。通过本综述，我们试图根据近期文献强调寡转移前列腺癌的治疗。
方法
在PubMed、Scopus和Embase上进行文献检索，使用关键词“寡转移”、“前列腺癌”，并使用“与”和“或”等运算符。筛选相关文章，本综述纳入了关于这个新兴实体的所有最新文章。
结果
纳入了所有与寡转移前列腺癌相关的试验，这些试验明确了手术、放疗和全身治疗的作用，并得出了适当的推论。相关研究以表格形式汇总在本文中。
结论
寡转移前列腺癌目前的标准治疗方案仍是遵循激素敏感性转移性前列腺癌的全身治疗。本文强调了手术、放疗以及全身治疗不断演变的作用。
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