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伴有震颤谵妄的酒精戒断

Alcohol Withdrawal with Delirium Tremens.

作者信息

Schwebach Courtney, Vempati Amrita

机构信息

Creighton University School of Medicine Phoenix Program, Valleyhealth Medical Center, Department of Emergency Medicine, Phoenix, AZ.

出版信息

J Educ Teach Emerg Med. 2023 Jul 31;8(3):S1-S33. doi: 10.21980/J8S35N. eCollection 2023 Jul.

Abstract

AUDIENCE

Emergency medicine (EM) residents (1 year and 2 year levels), 4th year medical students and advanced practice providers.

INTRODUCTION

Alcohol use has played a major role in causing significant morbidity and mortality for patients. In 2016, it was the 7th leading risk factor for deaths and disability-adjusted life years globally.1 Among heavy alcohol users admitted for hospital management, the incidence of alcohol withdrawal syndrome is estimated to be 1.9 to 6.7%.1 Alcohol withdrawal (AW) in the ED has been associated with increased use of critical care resources, and frequent ED visits for alcohol-related presentations have been associated with mortality rates that are about 1-4% when withdrawal progresses to delirium tremens (DTs).1 Patients with alcohol withdrawal can present in many different ways to the ED including anxiety, tachycardia, delirium tremens (DTs), seizures and severe autonomic dysfunction leading to severe sickness and death.2 Therefore, it is extremely important for an EM physician to recognize the signs of AW in patients and to manage the critically ill patients. In addition, Clinical Institute Withdrawal Assessment (CIWA) of alcohol was developed to assess severity of alcohol withdrawal in 1989.3 EM physicians should utilize CIWA to help determine the severity of AW.

EDUCATIONAL OBJECTIVES

By the end of the session, learner will be able to 1) discuss the causes of altered mental status, 2) utilize CIWA scoring system to quantify AW severity, 3) formulate appropriate treatment plan for AW by treating with benzodiazepine and escalating treatment appropriately, 4) treat electrolyte abnormalities by giving appropriate medications for hypokalemia and hypomagnesemia, and 5) discuss clinical progression and timing to AW.

EDUCATIONAL METHODS

This session was conducted using high-fidelity simulation, which was immediately followed by an in-depth debriefing session. The session was run during first year EM resident intern orientation, and it was run during two consecutive years. There was a total of 32 EM residents who participated. There was a total of 16 residents who actively managed the patient while the other 16 were observers. Each session had four learners and was run twice in two separate rooms. There was one simulation instructor running the session and one simulation technician who acted as a nurse.

RESEARCH METHODS

After the simulation and debriefing session was complete, an online survey was sent via surveymonkey.com to all the participants. The survey collected responses to the following questions: (1) the case was believable, (2) the case had right the amount of complexity (based on their Gestalt), (3) the case helped in improving medical knowledge and patient care, (4) the simulation environment gave me a real-life experience and, (5) the debriefing session after simulation helped improve my knowledge. The responses were collected using a Likert scale of 1 to 5 with 1 being "Strongly disagree" and 5 being "Strongly agree."

RESULTS

There was a total of 15 respondents from both years. One hundred percent of them either agreed or strongly agreed that the case was beneficial in learning, in improving medical knowledge and in patient care. All of them found the post-session debrief to be very helpful. Two of them felt neutral about the case being realistic. The median response for questions 1, 3 and 5 is 5. The median response for questions 2 and 4 was 4. The range of responses for questions 1, 2, 3 and 5 was 4-5 while the range for question 4 was 3-5.

DISCUSSION

This high-fidelity simulation was a cost-effective and realistic way of educating learners on how to manage AW with DTs. Learners are forced to start with a broad differential for the patient who presents with AMS. As they recognize the cause of mental status, the patient quickly decompensates into developing severe agitation and autonomic dysfunction requiring learners to manage the patient and establish an airway. Learners found the case to be beneficial in learning the management of AW.

TOPICS

Alcohol withdrawal, delirium tremens, agitation, altered mental status.

摘要

受众

急诊医学(EM)住院医师(1年级和2年级)、四年级医学生以及高级执业医疗人员。

引言

酒精使用在导致患者出现严重发病和死亡方面发挥了重要作用。2016年,它是全球第七大致死和伤残调整生命年的主要危险因素。在因需住院治疗而入院的重度酒精使用者中,酒精戒断综合征的发生率估计为1.9%至6.7%。急诊科的酒精戒断(AW)与重症监护资源使用增加有关,当戒断进展为震颤谵妄(DTs)时,因酒精相关症状频繁到急诊科就诊的患者死亡率约为1%至4%。酒精戒断患者可能以多种不同方式就诊于急诊科,包括焦虑、心动过速、震颤谵妄、癫痫发作以及导致严重疾病和死亡的严重自主神经功能障碍。因此,急诊医学医生识别患者酒精戒断的体征并管理重症患者极其重要。此外,1989年开发了酒精临床研究所戒断评估(CIWA)来评估酒精戒断的严重程度。急诊医学医生应利用CIWA来帮助确定酒精戒断的严重程度。

教育目标

课程结束时,学习者将能够:1)讨论精神状态改变的原因;2)利用CIWA评分系统量化酒精戒断的严重程度;3)通过使用苯二氮䓬类药物治疗并适当加强治疗,为酒精戒断制定合适的治疗方案;4)通过给予适当药物治疗低钾血症和低镁血症来治疗电解质异常;5)讨论酒精戒断的临床进展和时机。

教育方法

本课程采用高保真模拟进行,随后立即进行深入的总结汇报环节。该课程在急诊医学一年级住院医师实习迎新期间开展,连续两年进行。共有32名急诊医学住院医师参与。共有16名住院医师积极管理患者,另外16名是观察者。每次课程有四名学习者,在两个独立房间各进行两次。有一名模拟教员主持课程,一名模拟技术员扮演护士。

研究方法

模拟和总结汇报环节结束后,通过surveymonkey.com向所有参与者发送在线调查问卷。该调查收集了对以下问题的回答:(1)病例是否可信;(2)病例的复杂程度是否合适(基于他们的整体印象);(3)病例是否有助于提高医学知识和患者护理水平;(4)模拟环境是否给了我真实的体验;(5)模拟后的总结汇报环节是否有助于提高我的知识。回答采用1至5分的李克特量表收集,1分为“强烈不同意”,5分为“强烈同意”。

结果

两年共有15名受访者。他们100%同意或强烈同意该病例对学习、提高医学知识和患者护理有益。他们都认为课后总结汇报非常有帮助。其中两人对病例的真实性持中立态度。问题1、3和5的中位数回答为5分。问题2和4的中位数回答为4分。问题1、2、3和5的回答范围为4至5分,而问题4的回答范围为3至5分。

讨论

这种高保真模拟是一种经济有效的、真实的教育学习者如何管理伴有震颤谵妄的酒精戒断的方法。学习者必须从对出现意识改变的患者进行广泛鉴别诊断开始。当他们识别出精神状态的原因时,患者很快会出现严重的躁动和自主神经功能障碍,需要学习者管理患者并建立气道。学习者发现该病例对学习酒精戒断的管理有益。

主题

酒精戒断、震颤谵妄、躁动、意识改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fa5/10414982/af2a5395bb48/jetem-8-3-s1f2.jpg

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