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1例新冠病毒检测呈阳性且新诊断为糖尿病患者的侵袭性毛霉病病例报告

A Case Report of Invasive Mucormycosis in a COVID-19 Positive and Newly-Diagnosed Diabetic Patient.

作者信息

Davis Konnor, Almog Roy, Peleg Yuval, Spiegelman Lindsey

机构信息

University of California, Irvine, School of Medicine, Irvine, CA.

University of California, Irvine, Department of Emergency Medicine, Orange, CA.

出版信息

J Educ Teach Emerg Med. 2023 Jul 31;8(3):V10-V13. doi: 10.21980/J81M1G. eCollection 2023 Jul.

DOI:10.21980/J81M1G
PMID:37575409
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10414977/
Abstract

UNLABELLED

This is a case report of a 46-year-old female with undiagnosed diabetes, COVID-19, and mucormycosis. Mucormycosis is a rare, rapidly progressive disease process characterized by an insidious onset of vague symptoms and is associated with a high mortality rate. The patient initially presented at two outside ophthalmology clinics due to right eye pain and was prescribed steroids. Upon presentation to our institution's Emergency Department, the patient's pain had significantly increased along with new symptoms of ptosis and failure to adduct the right eye. Laboratory results demonstrated leukocytosis, hyperglycemia, and a positive SARS-CoV-2 test. Magnetic resonance imaging confirmed a diagnosis of mucormycosis and the patient underwent surgery and began intravenous antifungal therapy. This discussion addresses the presenting features of mucormycosis in the emergency department while highlighting the need for immediate investigation due to the fungi's rapidly progressive nature.

TOPICS

Mucormycosis, mucor, diabetes, COVID-19, ROCM.

摘要

未标注

这是一例关于一名46岁女性的病例报告,该女性患有未确诊的糖尿病、新冠肺炎和毛霉菌病。毛霉菌病是一种罕见的、进展迅速的疾病过程,其特征为隐匿起病的模糊症状,且死亡率很高。患者最初因右眼疼痛在两家外部眼科诊所就诊,并被开具了类固醇药物。在到我们机构的急诊科就诊时,患者的疼痛显著加剧,同时出现了上睑下垂和右眼内收障碍等新症状。实验室检查结果显示白细胞增多、血糖升高以及严重急性呼吸综合征冠状病毒2(SARS-CoV-2)检测呈阳性。磁共振成像确诊为毛霉菌病,患者接受了手术并开始静脉注射抗真菌治疗。本讨论阐述了急诊科毛霉菌病的表现特征,同时强调了由于真菌进展迅速,需要立即进行检查。

主题

毛霉菌病、毛霉、糖尿病、新冠肺炎、眼眶毛霉菌病

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/f973b89e6221/jetem-8-3-v10f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/4fcf1691681a/jetem-8-3-v10f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/b8b8493648fc/jetem-8-3-v10f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/f973b89e6221/jetem-8-3-v10f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/4fcf1691681a/jetem-8-3-v10f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/b8b8493648fc/jetem-8-3-v10f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea0d/10414977/f973b89e6221/jetem-8-3-v10f3.jpg

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本文引用的文献

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J Med Case Rep. 2022 Oct 31;16(1):400. doi: 10.1186/s13256-022-03594-2.
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Post COVID-19 rhinocerebral mucormycosis: a case report and literature review.新冠后鼻脑毛霉病:病例报告及文献复习。
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COVID-19 相关毛霉菌病的流行病学和发病机制:印度与世界其他地区。
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Rhinocerebral Mucormycosis and COVID-19 Pneumonia.鼻脑型毛霉菌病与新型冠状病毒肺炎
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