Noujaim Michael G, Tang Helen, Kalisz Kevin, Iranzad Natasha, Wild Daniel
Division of Gastroenterology, Duke University Medical Center, Durham, NC.
Department of Medicine, University of Pennsylvania Hospital, Philadelphia, PA.
ACG Case Rep J. 2023 Aug 11;10(8):e01125. doi: 10.14309/crj.0000000000001125. eCollection 2023 Aug.
Idiopathic myointimal hyperplasia of the mesenteric veins (IMHMV) is a rare and poorly understood noninflammatory ischemic colitis. First reported by Genta and Haggitt in 1991, the disease typically presents with chronic abdominal pain, weight loss, and diarrhea with or without hematochezia in middle-aged men. IMHMV is frequently misdiagnosed as an inflammatory bowel disease. The pathophysiology of IMHMV involves the proliferation of the intimal smooth muscle in mesenteric veins leading to bowel ischemia. The etiology of this process remains unknown. There are no good medical therapies for IMHMV, and surgical resection, a curative intervention, is typically required to make the diagnosis. We present the case of a 66-year-old man with IMHMV diagnosed with endoscopic biopsies.
肠系膜静脉特发性肌内膜增生（IMHMV）是一种罕见且了解甚少的非炎性缺血性结肠炎。1991年由根塔（Genta）和哈吉特（Haggitt）首次报道，该疾病通常表现为中年男性慢性腹痛、体重减轻以及伴有或不伴有便血的腹泻。IMHMV常被误诊为炎性肠病。IMHMV的病理生理学涉及肠系膜静脉内膜平滑肌增生导致肠缺血。这一过程的病因尚不清楚。对于IMHMV没有有效的药物治疗方法，通常需要手术切除这种治愈性干预措施来进行诊断。我们报告一例通过内镜活检诊断为IMHMV的66岁男性病例。
