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在主动监测中出现瘤内出血的脑膜瘤

Meningioma Presenting With Intratumoral Hemorrhage on Active Surveillance.

作者信息

Matias Rafael, Arantes Mavilde, Azevedo Júlia, Jacome Manuel, Aguiar Artur

机构信息

Radiation Oncology, Instituto Português de Oncologia do Porto Francisco Gentil, Porto, PRT.

Neuroradiology, Instituto Português de Oncologia do Porto Francisco Gentil, Porto, PRT.

出版信息

Cureus. 2023 Jul 12;15(7):e41787. doi: 10.7759/cureus.41787. eCollection 2023 Jul.

Abstract

Meningiomas are relatively common primary adult brain tumors. They are slow-growing, highly vascular, and graded according to histology, phenotypic and genotypic features. We present a case of a 66-year-old male with a history of tongue squamous cell carcinoma, which presented multiple risk factors for cardiovascular and thromboembolic events. A brain lesion was initially detected on a computed tomography (CT) scan and later characterized by magnetic resonance imaging (MRI). The multidisciplinary team decided to maintain surveillance due to the lack of associated symptoms. Upon expansion in size and acute intralesional hemorrhage seen on follow-up imaging, the patient was submitted to surgical excision. The histopathological testing determined it to be an atypical meningioma. Two months later, the patient received stereotactic radiotherapy, and a post-surgical MRI showed no evidence of tumor recurrence. This case report describes a rare occurrence of intratumoral hemorrhage in a meningioma during surveillance, highlighting the importance of vigilant monitoring and consideration of potential risk factors for hemorrhagic events.

摘要

脑膜瘤是相对常见的原发性成人大脑肿瘤。它们生长缓慢,血管丰富,并根据组织学、表型和基因型特征进行分级。我们报告一例66岁男性,有舌鳞状细胞癌病史,存在心血管和血栓栓塞事件的多种危险因素。最初在计算机断层扫描(CT)上检测到脑部病变,后来通过磁共振成像(MRI)进行了特征描述。由于缺乏相关症状,多学科团队决定进行监测。在随访成像中发现病变大小增大并伴有急性瘤内出血后,患者接受了手术切除。组织病理学检查确定为非典型脑膜瘤。两个月后,患者接受了立体定向放射治疗,术后MRI显示无肿瘤复发迹象。本病例报告描述了监测期间脑膜瘤罕见的瘤内出血情况,强调了警惕监测以及考虑出血事件潜在危险因素的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2957/10421599/d5fd10732a8b/cureus-0015-00000041787-i01.jpg

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