Abeloos L, Lefranc F
Service de neurochirurgie, hôpital Erasme, université Libre de Bruxelles (ULB), route de Lennik 808, Brussels, Belgium.
Neurochirurgie. 2011 Apr;57(2):78-81. doi: 10.1016/j.neuchi.2010.09.003. Epub 2011 May 4.
The growing use of magnetic resonance and computed tomography imaging has facilitated the diagnosis of brain tumours even before the presence of clinical signs. A significant proportion of incidental lesions identified will be meningiomas, i.e. more than 40% of the diagnosed meningiomas are not associated with clinical signs. The natural history of incidental asymptomatic intracranial meningiomas must be known to develop the optimal therapeutic strategy: what is the tumor growth rate? How many asymptomatic tumours eventually become symptomatic?
The literature was reviewed in an attempt to answer these questions.
In cases of incidental meningioma, its location, size and radiological aspect, the patient's age, the eventual unknown symptoms and the multiplicity of the lesions must all be considered. The radiological characteristics associated with low tumoral growth rate are the existence of calcifications and hypointense regions on T2-weighted MR images. On the radiological aspect, more than 60% of asymptomatic meningiomas will not grow in size. However, some meningiomas, even small in size, must be treated because of their location or the risk of producing neurological deficits.
We recommend neurosurgical consultation for all patients with an incidental meningioma.
磁共振成像和计算机断层扫描成像的使用日益增多,甚至在出现临床症状之前就有助于脑肿瘤的诊断。所发现的偶发性病变中有很大一部分将是脑膜瘤,即超过40%的已诊断脑膜瘤与临床症状无关。必须了解偶发性无症状颅内脑膜瘤的自然病史,以制定最佳治疗策略:肿瘤生长速度是多少?最终有多少无症状肿瘤会出现症状?
回顾文献以试图回答这些问题。
对于偶发性脑膜瘤病例,必须综合考虑其位置、大小、影像学表现、患者年龄、最终未知的症状以及病变的多发性。与低肿瘤生长速度相关的影像学特征是T2加权磁共振图像上存在钙化和低信号区域。从影像学角度来看,超过60%的无症状脑膜瘤大小不会增大。然而,一些脑膜瘤即使体积小,因其位置或产生神经功能缺损的风险也必须进行治疗。
我们建议所有患有偶发性脑膜瘤的患者进行神经外科会诊。