副肿瘤综合征诱发溃疡性结肠炎一例？
A Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome?
作者信息
Zhang Tao, Pan Zhu-Bin, Tong Wen-Jia, Zhou Yu-Liang, Cheng Yuan, Jin Dan-Qun, Qi Shi-Qin, Zhang Zhen-Qiang
机构信息
Department of General Surgery, Anhui Provincial Children's Hospital, Children's Hospital of Fudan University Anhui Hospital, Children's Hospital of Anhui Medical University, Hefei, 230000, People's Republic of China.
Department of Pediatric Intensive Care Unit, Anhui Provincial Children's Hospital, Children's Hospital of Fudan University Anhui Hospital, Children's Hospital of Anhui Medical University, Hefei, 230000, People's Republic of China.
出版信息
J Inflamm Res. 2023 Aug 8;16:3319-3327. doi: 10.2147/JIR.S418733. eCollection 2023.
BACKGROUND
Paraneoplastic syndromes often cause endocrine, neurological, cutaneous, and hematologic pathologies, and cases with digestive symptoms as prominent cases are rare.
CASE DESCRIPTION
A 1-year-old child admitted to the emergency department with severe abdominal distension was later diagnosed with sacrococcygeal yolk cystoma with ulcerative colitis. After symptomatic management, surgical removal of the tumor, and JEB chemotherapy, the symptoms of ulcerative colitis disappeared completely. After 7 years of follow-up, the child grew and developed well, and there was no recurrence of tumor and ulcerative colitis.
CONCLUSION
Yolk sac tumor with ulcerative colitis is a rare paraneoplastic syndrome with complex clinical manifestations.
背景
副肿瘤综合征常引起内分泌、神经、皮肤和血液系统病变，以消化症状为突出表现的病例罕见。
病例描述
一名1岁儿童因严重腹胀入住急诊科，后来被诊断为骶尾部卵黄囊瘤合并溃疡性结肠炎。经过对症处理、手术切除肿瘤以及JEB化疗后，溃疡性结肠炎症状完全消失。经过7年随访，患儿生长发育良好，肿瘤及溃疡性结肠炎均未复发。
结论
卵黄囊瘤合并溃疡性结肠炎是一种罕见的副肿瘤综合征，临床表现复杂。
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