• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

副肿瘤综合征诱发溃疡性结肠炎一例？

A Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome?

作者信息

Zhang Tao, Pan Zhu-Bin, Tong Wen-Jia, Zhou Yu-Liang, Cheng Yuan, Jin Dan-Qun, Qi Shi-Qin, Zhang Zhen-Qiang

机构信息

Department of General Surgery, Anhui Provincial Children's Hospital, Children's Hospital of Fudan University Anhui Hospital, Children's Hospital of Anhui Medical University, Hefei, 230000, People's Republic of China.

Department of Pediatric Intensive Care Unit, Anhui Provincial Children's Hospital, Children's Hospital of Fudan University Anhui Hospital, Children's Hospital of Anhui Medical University, Hefei, 230000, People's Republic of China.

出版信息

J Inflamm Res. 2023 Aug 8;16:3319-3327. doi: 10.2147/JIR.S418733. eCollection 2023.

DOI:10.2147/JIR.S418733
PMID:37576158
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10422985/
Abstract

BACKGROUND

Paraneoplastic syndromes often cause endocrine, neurological, cutaneous, and hematologic pathologies, and cases with digestive symptoms as prominent cases are rare.

CASE DESCRIPTION

A 1-year-old child admitted to the emergency department with severe abdominal distension was later diagnosed with sacrococcygeal yolk cystoma with ulcerative colitis. After symptomatic management, surgical removal of the tumor, and JEB chemotherapy, the symptoms of ulcerative colitis disappeared completely. After 7 years of follow-up, the child grew and developed well, and there was no recurrence of tumor and ulcerative colitis.

CONCLUSION

Yolk sac tumor with ulcerative colitis is a rare paraneoplastic syndrome with complex clinical manifestations.

摘要

背景

副肿瘤综合征常引起内分泌、神经、皮肤和血液系统病变，以消化症状为突出表现的病例罕见。

病例描述

一名1岁儿童因严重腹胀入住急诊科，后来被诊断为骶尾部卵黄囊瘤合并溃疡性结肠炎。经过对症处理、手术切除肿瘤以及JEB化疗后，溃疡性结肠炎症状完全消失。经过7年随访，患儿生长发育良好，肿瘤及溃疡性结肠炎均未复发。

结论

卵黄囊瘤合并溃疡性结肠炎是一种罕见的副肿瘤综合征，临床表现复杂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/e6ca4da3b64c/JIR-16-3319-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/506149a770a7/JIR-16-3319-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/d94ec07fed49/JIR-16-3319-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/b943083d28c0/JIR-16-3319-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/511cb30d327c/JIR-16-3319-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/13e2a061675e/JIR-16-3319-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/e6ca4da3b64c/JIR-16-3319-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/506149a770a7/JIR-16-3319-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/d94ec07fed49/JIR-16-3319-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/b943083d28c0/JIR-16-3319-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/511cb30d327c/JIR-16-3319-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/13e2a061675e/JIR-16-3319-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/00a2/10422985/e6ca4da3b64c/JIR-16-3319-g0006.jpg

相似文献

1
A Case of Ulcerative Colitis Induced by Paraneoplastic Syndrome?副肿瘤综合征诱发溃疡性结肠炎一例？
J Inflamm Res. 2023 Aug 8;16:3319-3327. doi: 10.2147/JIR.S418733. eCollection 2023.
2
[Fatal toxic megacolon due to cytomegalovirosis in a patient with ulcerative colitis: case report and review].[一名溃疡性结肠炎患者因巨细胞病毒感染导致致命性中毒性巨结肠：病例报告及文献复习]
Arq Gastroenterol. 2002 Apr-Jun;39(2):111-3. doi: 10.1590/s0004-28032002000200008. Epub 2003 Feb 19.
3
Successful treatment of ulcerative colitis complicated by Sweet's syndrome by corticosteroid therapy and leukocytapheresis.通过皮质类固醇疗法和白细胞去除术成功治疗溃疡性结肠炎合并Sweet综合征。
Clin J Gastroenterol. 2011 Jun;4(3):151-156. doi: 10.1007/s12328-011-0215-z. Epub 2011 Mar 29.
4
TOXIC MEGACOLON IN ULCERATIVE COLITIS.溃疡性结肠炎中的中毒性巨结肠
Can Med Assoc J. 1964 Feb 1;90(5):357-63.
5
A patient who survived total colonic ulcerative colitis surinfected by cytomegalovirus complicated by toxic megacolon and disseminated intravascular coagulation.一名全结肠溃疡性结肠炎幸存者感染了巨细胞病毒，并发中毒性巨结肠和弥散性血管内凝血。
Acta Gastroenterol Belg. 2005 Apr-Jun;68(2):276-9.
6
Outcome following emergency surgery for refractory severe ulcerative colitis in a tertiary care centre in India.印度一家三级医疗中心难治性重症溃疡性结肠炎急诊手术后的结果
BMC Gastroenterol. 2005 Nov 30;5:39. doi: 10.1186/1471-230X-5-39.
7
[Severe acute colitis: two fatal cases in Dakar].[重症急性结肠炎：达喀尔的两例死亡病例]
Med Sante Trop. 2014 Oct-Dec;24(4):438-40. doi: 10.1684/mst.2014.0375.
8
Toxic megacolon in Salmonella colitis: report of two cases.沙门氏菌结肠炎所致中毒性巨结肠：两例报告
Acta Paediatr Taiwan. 2000 Jan-Feb;41(1):43-6.
9
A Rare Case of Signet Cell Carcinoma of Transverse Colon in a Young Patient With Ulcerative Colitis.一名患有溃疡性结肠炎的年轻患者发生横结肠印戒细胞癌的罕见病例。
J Med Cases. 2020 May;11(5):135-139. doi: 10.14740/jmc3469. Epub 2020 May 3.
10
Toxic megacolon of ulcerative colitis in infancy.婴儿期溃疡性结肠炎所致中毒性巨结肠
Pediatrics. 1976 Jun;57(6):962-6.

本文引用的文献

1
Dual Biologic Therapy in Moderate to Severe Pediatric Inflammatory Bowel Disease: A Retrospective Study.中度至重度小儿炎症性肠病的双生物制剂疗法：一项回顾性研究
Children (Basel). 2022 Dec 21;10(1):11. doi: 10.3390/children10010011.
2
The Association of Inflammatory Bowel Disease with Coeliac Disease and Coeliac Autoimmunity in Children and Adults: A Nationwide Study from the epi-IIRN.炎症性肠病与儿童和成人乳糜泻及乳糜泻自身免疫的关联：来自 epi-IIRN 的全国性研究。
J Crohns Colitis. 2023 May 3;17(5):700-705. doi: 10.1093/ecco-jcc/jjac176.
3
Perioperative Management of Ulcerative Colitis: A Systematic Review.
溃疡性结肠炎的围手术期处理：系统评价。
Dis Colon Rectum. 2022 Dec 1;65(S1):S5-S19. doi: 10.1097/DCR.0000000000002588.
4
Diagnostic Delay in Pediatric Inflammatory Bowel Disease: A Systematic Review.儿科炎症性肠病的诊断延误：系统评价。
Dig Dis Sci. 2022 Dec;67(12):5444-5454. doi: 10.1007/s10620-022-07452-5. Epub 2022 Mar 14.
5
Pure yolk sac tumor of sacrococcygeal region.骶尾部纯卵黄囊瘤。
Autops Case Rep. 2021 May 25;11:e2021287. doi: 10.4322/acr.2021.287. eCollection 2021.
6
Review of paraneoplastic syndromes in children.儿童副肿瘤综合征综述
Pediatr Radiol. 2019 Apr;49(4):534-550. doi: 10.1007/s00247-019-04371-y. Epub 2019 Mar 16.
7
Bazex Syndrome with Hypoalbuminemia and Severe Ascites.伴有低白蛋白血症和严重腹水的巴泽克斯综合征
Case Rep Oncol. 2016 Jul 29;9(2):405-408. doi: 10.1159/000448168. eCollection 2016 May-Aug.
8
Atypical presentation of sacrococcygeal yolk sac tumor in infant: beware of the injuries of the gluteal region.婴儿骶尾部卵黄囊瘤的非典型表现：警惕臀区损伤。
J Ultrasound. 2014 Dec 13;19(3):227-9. doi: 10.1007/s40477-014-0147-9. eCollection 2016 Sep.
9
Autoimmune blistering dermatoses as systemic diseases.自身免疫性大疱性皮肤病作为系统性疾病
Clin Dermatol. 2014 May-Jun;32(3):364-75. doi: 10.1016/j.clindermatol.2013.11.003. Epub 2013 Nov 22.
10
ESPGHAN revised porto criteria for the diagnosis of inflammatory bowel disease in children and adolescents.欧洲儿科胃肠病、肝病和营养学会（ESPGHAN）修订了儿童和青少年炎症性肠病的诊断标准。
J Pediatr Gastroenterol Nutr. 2014 Jun;58(6):795-806. doi: 10.1097/MPG.0000000000000239.