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青少年酒精相关伤害的社会经济不平等:对68299名丹麦15至19岁青少年的前瞻性队列研究。

Socioeconomic inequalities in alcohol-related harm in adolescents: a prospective cohort study of 68,299 Danish 15-19-year-olds.

作者信息

Tolstrup Janne S, Kruckow Sofie, Becker Ulrik, Andersen Ove, Sawyer Susan M, Katikireddi Srinivasa Vittal, Møller Sanne Pagh

机构信息

National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.

Department of Clinical Research, Copenhagen University Hospital Amager and Hvidovre, Hvidovre, Denmark.

出版信息

EClinicalMedicine. 2023 Aug 3;62:102129. doi: 10.1016/j.eclinm.2023.102129. eCollection 2023 Aug.

Abstract

BACKGROUND

Evidence shows that similar levels of alcohol consumption lead to greater harm in adults with low socioeconomic position (SEP) compared to high SEP. We investigated if SEP is associated with alcohol-related hospital contacts in adolescents, and whether differences in risk can be explained by differences in levels of alcohol consumption, drinking pattern, and substance use.

METHODS

This is a prospective cohort study of 68,299 participants aged 15-19 years old from the Danish National Youth Cohort 2014. SEP was operationalised as parent educational level, family income and perceived financial strain in the family. Data were linked to national registers and participants were followed up for five years from 2014 to 2019. Outcomes were hospital contacts due to alcohol. Multilevel Poisson regression was used to estimate incidence rates (IR) and incidence rate ratios (IRR).

FINDINGS

During 280,010 person years of follow-up, 872 participants had an alcohol-attributable hospital contact; intoxications (n = 778, 89%) were the most common diagnosis. Low as compared to high SEP was associated with higher IRR of alcohol-attributable hospital contacts for all three SEP measures. The adjusted IRR of harm was 1.73 (95% CI: 1.29-2.33) for elementary school as the highest parent education compared to longer parent education and 1.57 (95% CI: 1.30-1.89) for family financial strain compared to those without financial strain. Adjustment for weekly alcohol intake, drinking pattern and substance use did not substantially change results. Cubic spline analysis of the association between family income and alcohol-attributable hospital contacts revealed a dose-response relationship with decreasing risk of alcohol-related harm with higher income.

INTERPRETATION

Our findings suggested that alcohol-related harm is more common in socioeconomically disadvantaged adolescents despite similar levels of alcohol consumption, regardless of differences in drinking pattern or substance use. Future preventive strategies should prioritise young adolescents, including those who are most disadvantaged.

FUNDING

Tryg Foundation (ID: 153539).

摘要

背景

有证据表明,与社会经济地位较高的成年人相比,社会经济地位较低(SEP)的成年人在饮酒量相似的情况下会受到更大的伤害。我们调查了SEP是否与青少年与酒精相关的住院情况有关,以及风险差异是否可以通过饮酒量、饮酒模式和物质使用的差异来解释。

方法

这是一项对丹麦2014年全国青年队列中68299名15至19岁参与者进行的前瞻性队列研究。SEP通过父母教育水平、家庭收入和家庭中感知到的经济压力来衡量。数据与国家登记册相关联,参与者从2014年到2019年进行了五年的随访。结果是因酒精导致的住院情况。采用多水平泊松回归来估计发病率(IR)和发病率比(IRR)。

结果

在280010人年的随访期间,872名参与者有与酒精相关的住院情况;中毒(n = 778,89%)是最常见的诊断。与高SEP相比,低SEP在所有三种SEP衡量指标上都与酒精相关住院情况的更高IRR相关。与父母受教育时间较长相比,父母最高教育水平为小学时伤害的调整后IRR为1.73(95%CI:1.29 - 2.33),与没有经济压力的家庭相比,家庭经济压力时的调整后IRR为1.57(95%CI:1.30 - 1.89)。对每周饮酒量、饮酒模式和物质使用进行调整后,结果没有实质性变化。对家庭收入与酒精相关住院情况之间关联的三次样条分析显示,随着收入增加,与酒精相关伤害风险降低呈剂量反应关系。

解读

我们的研究结果表明,尽管饮酒量相似,但社会经济处于不利地位的青少年中与酒精相关的伤害更为常见,无论饮酒模式或物质使用有无差异。未来的预防策略应优先考虑青少年,包括那些最处于不利地位的青少年。

资助

Tryg基金会(ID:153539)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3775/10415833/368c6cfa0203/gr1.jpg

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