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一名轻度新冠病毒检测呈阳性患者出现灾难性动静脉血栓形成

Catastrophic Concomitant Arterial and Venous Thrombosis in a Mild COVID-19-Positive Patient.

作者信息

Nugraha Raka A, Muliawan Hary S, Nugroho Nyityasmono T, Ikhsan Muhammad, Adiarto Suko

机构信息

Department of General Medicine, Universitas Indonesia Hospital, Depok, Indonesia.

Department of Cardiology and Vascular Medicine, National Cardiovascular Center Harapan Kita/Universitas Indonesia Hospital, Depok, Indonesia.

出版信息

Int J Angiol. 2021 Oct 1;32(3):197-201. doi: 10.1055/s-0041-1735200. eCollection 2023 Sep.

Abstract

Since its first discovery in late 2019, coronavirus disease 2019 (COVID-19) has been a global burden associated with significant morbidity and mortality. COVID-19 has been correlated with the development of hypercoagulable state that predisposes the patients to a higher risk of thromboembolism. Current evidence suggests higher incidence of thrombosis, particularly venous thrombosis, among hospitalized COVID-19 patients, mostly with critical illness. On the other hand, there is currently no data regarding the incidence of vivid thrombosis in ambulatory patients with mild COVID-19 and the incidence of concomitant arterial and venous thrombosis in COVID-19 is extremely rare. Herein, we describe catastrophic outcomes of concomitant lower limb arterial and venous thrombosis in a patient with mild COVID-19. This report highlights the occurrence of concomitant arterial and venous thrombosis in ambulatory setting and that this phenomenon resulted in catastrophic clinical consequences.

摘要

自2019年末首次发现以来,2019冠状病毒病(COVID-19)一直是一个全球性负担,伴随着显著的发病率和死亡率。COVID-19与高凝状态的发展相关,这使患者更容易发生血栓栓塞。目前的证据表明,住院的COVID-19患者,尤其是危重症患者,血栓形成的发生率更高,尤其是静脉血栓形成。另一方面,目前尚无关于轻症COVID-19门诊患者发生动静脉血栓形成的发生率的数据,且COVID-19患者同时发生动脉和静脉血栓形成的情况极为罕见。在此,我们描述了一名轻症COVID-19患者同时发生下肢动脉和静脉血栓形成的灾难性后果。本报告强调了在门诊环境中同时发生动脉和静脉血栓形成的情况,以及这一现象导致的灾难性临床后果。

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本文引用的文献

1
Acute limb ischemia in a COVID-19 patient.一名新冠肺炎患者的急性肢体缺血
Thromb Update. 2021;2:100031. doi: 10.1016/j.tru.2020.100031. Epub 2021 Mar 19.
6
COVID-19 and Hypercoagulability: A Review.新型冠状病毒肺炎与高凝状态:综述
Clin Appl Thromb Hemost. 2020 Jan-Dec;26:1076029620962853. doi: 10.1177/1076029620962853.
8
Bilateral Acute Lower Limb Ischemia Secondary to COVID-19.双侧急性下肢缺血继发于 COVID-19。
Vasc Endovascular Surg. 2021 Feb;55(2):196-199. doi: 10.1177/1538574420954301. Epub 2020 Sep 10.

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