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First-line management of advanced non-small-cell lung cancer: can we do better?

作者信息

Chouaïd Christos, Monnet Isabelle, Auliac Jean-Bernard

机构信息

Service de Pneumologie, CHI Créteil, Créteil, France.

Inserm U955, UPEC, IMRB, Créteil, France.

出版信息

Transl Lung Cancer Res. 2023 Jul 31;12(7):1643-1648. doi: 10.21037/tlcr-23-200. Epub 2023 Jun 1.

DOI:10.21037/tlcr-23-200
PMID:37577310
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10413041/
Abstract
摘要

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本文引用的文献

1
First-line atezolizumab monotherapy versus single-agent chemotherapy in patients with non-small-cell lung cancer ineligible for treatment with a platinum-containing regimen (IPSOS): a phase 3, global, multicentre, open-label, randomised controlled study.一线阿特珠单抗单药治疗与含铂方案治疗不适用的非小细胞肺癌患者的单药化疗（IPSOS）：一项全球、多中心、开放标签、随机对照的 3 期临床试验。
Lancet. 2023 Aug 5;402(10400):451-463. doi: 10.1016/S0140-6736(23)00774-2. Epub 2023 Jul 6.
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Pembrolizumab Plus Pemetrexed and Platinum in Nonsquamous Non-Small-Cell Lung Cancer: 5-Year Outcomes From the Phase 3 KEYNOTE-189 Study.帕博利珠单抗联合培美曲塞和铂类化疗用于非鳞状非小细胞肺癌：III 期 KEYNOTE-189 研究的 5 年结果。
J Clin Oncol. 2023 Apr 10;41(11):1992-1998. doi: 10.1200/JCO.22.01989. Epub 2023 Feb 21.
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First-line nivolumab plus ipilimumab for metastatic non-small cell lung cancer, including patients with ECOG performance status 2 and other special populations: CheckMate 817.纳武利尤单抗联合伊匹木单抗一线治疗转移性非小细胞肺癌，包括 ECOG 体能状态 2 分及其他特殊人群：CheckMate 817 研究
J Immunother Cancer. 2023 Feb;11(2). doi: 10.1136/jitc-2022-006127.
4
Durvalumab With or Without Tremelimumab in Combination With Chemotherapy as First-Line Therapy for Metastatic Non-Small-Cell Lung Cancer: The Phase III POSEIDON Study.度伐利尤单抗联合或不联合替西木单抗联合化疗作为转移性非小细胞肺癌一线治疗的 III 期 POSEIDON 研究。
J Clin Oncol. 2023 Feb 20;41(6):1213-1227. doi: 10.1200/JCO.22.00975. Epub 2022 Nov 3.
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NEPTUNE: Phase 3 Study of First-Line Durvalumab Plus Tremelimumab in Patients With Metastatic NSCLC.海王星研究：度伐利尤单抗联合曲美木单抗一线治疗转移性非小细胞肺癌的3期研究。
J Thorac Oncol. 2023 Jan;18(1):106-119. doi: 10.1016/j.jtho.2022.09.223. Epub 2022 Oct 12.
6
Five-Year Survival Outcomes With Nivolumab Plus Ipilimumab Versus Chemotherapy as First-Line Treatment for Metastatic Non-Small-Cell Lung Cancer in CheckMate 227.纳武利尤单抗联合伊匹单抗对比化疗作为一线治疗用于 CheckMate 227 研究转移性非小细胞肺癌的 5 年生存结果。
J Clin Oncol. 2023 Feb 20;41(6):1200-1212. doi: 10.1200/JCO.22.01503. Epub 2022 Oct 12.
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Cemiplimab plus chemotherapy versus chemotherapy alone in non-small cell lung cancer: a randomized, controlled, double-blind phase 3 trial.西妥昔单抗联合化疗对比单纯化疗治疗非小细胞肺癌：一项随机、对照、双盲的 3 期临床试验。
Nat Med. 2022 Nov;28(11):2374-2380. doi: 10.1038/s41591-022-01977-y. Epub 2022 Aug 25.
8
First-line single-agent pembrolizumab for PD-L1-positive (tumor proportion score ≥ 50%) advanced non-small cell lung cancer in the real world: impact in brain metastasis: a national French multicentric cohort (ESCKEYP GFPC study).一线单药帕博利珠单抗治疗 PD-L1 阳性（肿瘤比例评分≥50%）的晚期非小细胞肺癌的真实世界研究：脑转移的影响：一项全国性的法国多中心队列研究（ESCKEYP GFPC 研究）。
Cancer Immunol Immunother. 2023 Jan;72(1):91-99. doi: 10.1007/s00262-022-03232-2. Epub 2022 Jun 21.
9
Association between the baseline tumor size and outcomes of patients with non-small cell lung cancer treated with first-line immune checkpoint inhibitor monotherapy or in combination with chemotherapy.一线免疫检查点抑制剂单药治疗或联合化疗的非小细胞肺癌患者基线肿瘤大小与预后的关联
Transl Lung Cancer Res. 2022 Feb;11(2):135-149. doi: 10.21037/tlcr-21-815.
10
Association of tumour burden with the efficacy of programmed cell death-1/programmed cell death ligand-1 inhibitors for treatment-naïve advanced non-small-cell lung cancer.肿瘤负担与治疗初治晚期非小细胞肺癌的程序性细胞死亡受体 1/程序性细胞死亡配体 1 抑制剂疗效的关系。
Eur J Cancer. 2022 Jan;161:44-54. doi: 10.1016/j.ejca.2021.11.011. Epub 2021 Dec 15.