Stratta P, Canavese C, Messina M, Colla L, Dogliani M, Vercellone A
Drug Alcohol Depend. 1986 Jul;17(4):377-80. doi: 10.1016/0376-8716(86)90088-8.
Renal diseases occur in intravenous drug abusers, especially heroin addicts, in the form of interstitial nephritis, nephrotic syndrome or acute renal failure due to rhabdomyolysis. We report a case of acute renal failure not ascribable to rhabdomyolysis nor to the main pathogenetic mechanisms of pregnancy-related acute renal failure in a pregnant heroin addict woman after vaginal delivery following uncomplicated pregnancy. Drug-related immunological abnormalities and microcirculatory distress may be involved.
肾脏疾病在静脉注射吸毒者中较为常见,尤其是海洛因成瘾者,表现为间质性肾炎、肾病综合征或横纹肌溶解导致的急性肾衰竭。我们报告了一例急性肾衰竭病例,该病例既不能归因于横纹肌溶解,也不能归因于与妊娠相关的急性肾衰竭的主要发病机制。患者为一名怀孕的海洛因成瘾女性,孕期无并发症,经阴道分娩后出现急性肾衰竭。可能涉及与药物相关的免疫异常和微循环障碍。