长期口服强力霉素治疗后圈养大角羊（加拿大盘羊）中绵羊肺炎支原体的清除情况

Clearance of Mycoplasma ovipneumoniae in Captive Bighorn Sheep (Ovis canadensis) Following Extended Oral Doxycycline Treatment.

作者信息

Wood Mary E, Edwards William H, Jennings-Gaines Jessica E, Gaston Mariah, Van Wick Peach, Amundson Sierra, Allen Samantha E, Wolfe Lisa L

机构信息

Colorado Parks and Wildlife, Wildlife Health Program, 4330 Laporte Ave., Fort Collins, Colorado 80521, USA.

Wyoming Game and Fish Department, Veterinary Services, 1212 S. Adams St., Laramie, Wyoming 82070, USA.

出版信息

J Wildl Dis. 2023 Oct 1;59(4):753-758. doi: 10.7589/JWD-D-22-00094.

DOI:10.7589/JWD-D-22-00094

PMID:37578752

Abstract

Respiratory disease is a significant barrier for bighorn sheep (Ovis canadensis) conservation, and a need remains for management options in both captive and free-ranging populations. We treated Mycoplasma ovipneumoniae infection in six bighorn lambs and five bighorn yearlings at two captive research facilities with twice daily oral doxycycline for 8 wk or longer. Doses of 5 mg/kg twice daily mixed in formula for lambs and 10 mg/kg twice daily mixed in moistened pellets for older lambs and yearlings were tolerated well with minimal side effects. All animals in this case report remain Mycoplasma ovipneumoniae free over 2 yr later. Further evaluation is warranted to confirm efficacy of this therapeutic approach.

摘要

呼吸系统疾病是大角羊（加拿大盘羊）保护工作的一个重大障碍，无论是圈养还是野生种群，都仍然需要管理方案。我们在两个圈养研究设施中，对6只大角羊羔羊和5只大角羊一岁羊进行了支原体性肺炎感染治疗，每天口服强力霉素两次，持续8周或更长时间。羔羊每天两次5mg/kg混于配方奶中，年长羔羊和一岁羊每天两次10mg/kg混于湿润颗粒饲料中，耐受性良好，副作用最小。本病例报告中的所有动物在两年多后仍未感染支原体性肺炎。有必要进行进一步评估以确认这种治疗方法的疗效。