Besser Thomas E, Cassirer E Frances, Yamada Catherine, Potter Kathleen A, Herndon Caroline, Foreyt William J, Knowles Donald P, Srikumaran Subramaniam
Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, Washington 99164-7040, USA.
J Wildl Dis. 2012 Jan;48(1):168-72. doi: 10.7589/0090-3558-48.1.168.
To test the hypothesis that Mycoplasma ovipneumoniae is an important agent of the bighorn sheep (Ovis canadensis) pneumonia that has previously inevitably followed experimental commingling with domestic sheep (Ovis aries), we commingled M. ovipneumoniae-free domestic and bighorn sheep (n=4 each). One bighorn sheep died with acute pneumonia 90 days after commingling, but the other three remained healthy for >100 days. This unprecedented survival rate is significantly different (P=0.002) from that of previous bighorn-domestic sheep contact studies but similar to (P>0.05) bighorn sheep survival following commingling with other ungulates. The absence of epizootic respiratory disease in this experiment supports the hypothesized role of M. ovipneumoniae as a key pathogen of epizootic pneumonia in bighorn sheep commingled with domestic sheep.
绵羊肺炎支原体是大角羊（加拿大盘羊）肺炎的重要病原体，此前大角羊与家羊（绵羊）进行实验性混群后不可避免地会出现肺炎，我们将无绵羊肺炎支原体的家羊和大角羊混群（每组4只）。混群90天后，一只大角羊死于急性肺炎，但其他三只健康存活超过100天。这一前所未有的存活率与之前大角羊与家羊接触研究的存活率显著不同（P = 0.002），但与大角羊与其他有蹄类动物混群后的存活率相似（P>0.05）。本实验中没有出现流行性呼吸道疾病，支持了绵羊肺炎支原体作为与家羊混群的大角羊流行性肺炎关键病原体的假说。
