[Effect of the Japanese cucumaria on phospholipid metabolism in the liver of mice with solid Ehrlich carcinoma].

Japan cucumaria possesses an inhibitory action on the solid Ehrlich adenocarcinoma. The optimum dose, 15000 mg/kg, is established which provides a 46.49% of the growth inhibiting. The delay of the malignant process development is followed by normalization on phospholipid metabolism in the liver of tumour-bearing mice: the contents of phosphatidylcholine reached the normal level, the contents of sphingomyelin decreased, a portion of lysophosphatidylcholine and lysophosphatidylethanolamine was considerably reduced. The results obtained show that certain doses of cucumaria improve metabolic processes in the liver.