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铒钇铝石榴石(Er:YAG)激光:对部分睡眠呼吸障碍患者的一种微创治疗方法——4年后治疗效果评估

Erbium:Yttrium Aluminum Garnet (Er:YAG) Laser: A Minimally Invasive Treatment Method in Selected Patients with Impaired Breathing During Sleep-The Assessment of Treatment Effectiveness After 4 Years.

作者信息

Frelich Henryk, Marków Magdalena, Tażbirek Maciej, Frelich-Truchel Hanna, Misiołek Maciej, Ścierski Wojciech

机构信息

Specialist Dental Center A.H. Frelich Żory, Katowice, Poland.

Department of Otorhinolaryngology and Laryngological Oncology in Zabrze, Medical University of Silesia, Katowice, Poland.

出版信息

Photobiomodul Photomed Laser Surg. 2023 Aug;41(8):415-421. doi: 10.1089/photob.2022.0144.

Abstract

The aim of this study was to assess the long-term outcomes of nonablative Er:YAG laser treatment for snoring. Nonablative Er:YAG laser treatment has been shown to improve subjective quality of sleep without serious adverse effects, but long-term data are lacking. Twenty-four patients with snoring problems due to soft palate hypertrophy were treated with three treatment procedures with Er:YAG laser performed at 2-week intervals. Subjective (questionnaires) and objective (polygraph) outcome measures were assessed at baseline, 3 months, and 4 years after the final laser treatment. Twenty patients returned for the 4 years follow-up. The significant improvement in subjective sleep outcomes observed 3 months after Er:YAG laser treatment was still significant 4 years after treatment. No significant improvement or deterioration in objective polygraph outcome measures was observed during the 4 years of follow-up in our study. No side effects of laser treatment were observed. The Er:YAG laser treatment presents a safe and well-tolerated snoring treatment alternative for patients with airway obstruction in the oropharynx with improvement in subjective sleep outcomes lasting up to 4 years.

摘要

本研究的目的是评估非消融性铒激光治疗打鼾的长期效果。非消融性铒激光治疗已被证明可改善主观睡眠质量且无严重不良反应,但缺乏长期数据。24例因软腭肥大导致打鼾问题的患者接受了3次铒激光治疗,治疗间隔为2周。在基线、最后一次激光治疗后3个月和4年时评估主观(问卷调查)和客观(多导睡眠监测)结果指标。20例患者返回进行4年随访。铒激光治疗3个月后观察到的主观睡眠结果的显著改善在治疗4年后仍然显著。在我们的研究随访的4年中,客观多导睡眠监测结果指标未观察到显著改善或恶化。未观察到激光治疗的副作用。铒激光治疗为口咽气道阻塞患者提供了一种安全且耐受性良好的打鼾治疗选择,可改善主观睡眠结果,且持续长达4年。

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