Teixeira Clara Andrade, Morais Ana Normélia Pereira de, Moura Gabriel Acácio de, Gomes Isadora de Almeida, Souza Sabrina Vieira de, Dias Mônica Odilha Magalhães, Lima Ana Beatriz Rocha, Monteiro Paula Bruno
Christus University Center (UNICHRISTUS), Fortaleza-CE, Brazil.
Laboratory of Manipulation of Oocytes and Preantral Follicles, Post-Graduate Program in Physiological Sciences (PPGCF), State University of Ceará (UECE), Fortaleza-CE, Brazil.
JBRA Assist Reprod. 2023 Aug 14;27(4):709-16. doi: 10.5935/1518-0557.20230024.
To verify from a systematic literature review the possible effects of thyroid diseases on assisted reproduction techniques.
The studies were analyzed from the PubMed, Cochrane Library, LILACS databases.
The articles selected for the review included: cross-sectional studies, cohort studies, and clinical trials that addressed the proposed theme and which were published within the period stipulated from January 1, 2012, to March 5, 2022, in English, Portuguese and Spanish. These would later have to go through stages of inclusion as a framework of the type of study and exclusion criteria that were review articles, case reports, abstracts, articles with animal models, and duplicate articles and letters to the editor.
Author's name; Number of patients; Clinical outcome; Use of drugs; Control group (in case it had); Clinical outcome.
In in vitro fertilization and intracytoplasmic sperm injection it was verified that thyroid diseases can lead to effects such as a reduction in the rate of recovered oocytes, a decrease in the number of embryos, lower pregnancy rates, and increased chances of congenital anomalies in these patients and a reduction in the rate of implantation. Levothyroxine can increase the number of cycle cancellations.
Thyroid diseases may have deleterious effects on the clinical outcome of in vitro fertilization and intracytoplasmic sperm injection.
通过系统的文献综述验证甲状腺疾病对辅助生殖技术可能产生的影响。
从PubMed、Cochrane图书馆、LILACS数据库中分析相关研究。
纳入综述的文章包括：横断面研究、队列研究和临床试验，这些研究涉及所提出的主题，且于2012年1月1日至2022年3月5日期间以英文、葡萄牙文和西班牙文发表。这些文章随后必须经过纳入阶段，作为研究类型框架以及排除标准，即综述文章、病例报告、摘要、有动物模型的文章、重复文章以及给编辑的信件。
作者姓名；患者数量；临床结果；药物使用情况；对照组（若有）；临床结果。
在体外受精和卵胞浆内单精子注射中，已证实甲状腺疾病可导致以下影响，如回收的卵母细胞率降低、胚胎数量减少、妊娠率降低、这些患者先天性异常的几率增加以及着床率降低。左甲状腺素可增加周期取消率。
甲状腺疾病可能对体外受精和卵胞浆内单精子注射的临床结果产生有害影响。
