Yoshida M, Ide H, Yamada A, Endo M
Endoscopy. 1986 Sep;18 Suppl 3:44-8. doi: 10.1055/s-2007-1018441.
Fifty-two cases of primary adenocarcinoma of the esophagus were studied with respect to their origin and features in the early stage. The origin of the tumor was determined in 12 cases. Six cases arose in Barrett's esophagus, 5 cases in esophageal glands, and one case in ectopic gastric mucosa. The postoperative prognosis was closely related to the invasion to the adventitia. Tumors with no adventitial invasion showed excellent results, and their early detection is recommended. Submucosal tumors arising in Barrett's epithelium or in leading ducts of esophageal glands presented as small elevated lesions at endoscopy. On the other hand, tumors arising in submucosal glands showed diffuse infiltration into the esophageal wall and were difficult to detect in the early stage. Endoscopic examination aided by the staining method or brush cytology is recommended.
对52例原发性食管腺癌的起源及早期特征进行了研究。确定了12例肿瘤的起源。6例起源于巴雷特食管，5例起源于食管腺，1例起源于异位胃黏膜。术后预后与外膜侵犯密切相关。无外膜侵犯的肿瘤预后良好，建议早期发现。起源于巴雷特上皮或食管腺主导管的黏膜下肿瘤在内镜检查时表现为小的隆起性病变。另一方面，起源于黏膜下腺的肿瘤表现为向食管壁的弥漫性浸润，早期难以发现。建议采用染色法或刷检细胞学辅助内镜检查。
