Universidade Federal de Pernambuco, Centro de Ciências da Saúde, Recife, PE, Brazil.
Universidade Federal de Pernambuco, Centro de Ciências da Saúde, Recife, PE, Brazil.
Braz J Otorhinolaryngol. 2023 Sep-Oct;89(5):101300. doi: 10.1016/j.bjorl.2023.101300. Epub 2023 Jul 19.
To determine the cut-off point of the cochlear radiation dose as a risk factor for hearing loss in patients with vestibular schwannoma treated with radiosurgery.
A systematic review of the literature was performed without language or publication year restrictions in the MEDLINE/PubMed, EMBASE, Web of Science, LILACS/VHL and Cochrane Library databases. Studies that met the following criteria were included: 1) population: adults of both sexes who underwent radiosurgery for vestibular schwannoma treatment; 2) exposure: cochlear radiation; 3) outcome: hearing loss; 4) type of study: cohort. Two independent reviewers conducted the entire review process. The registration number in PROSPERO was CRD42020206128.
From the 333 articles identified in the searches, seven were included after applying the eligibility criteria. There was no standardization as to how to measure exposure or outcome in the included studies, and most studies did not present sufficient data to enable meta-analysis.
It was not possible to determine a cut-off point for high cochlear dose that could be considered a risk factor for hearing loss.
确定耳蜗辐射剂量作为接受放射外科治疗的前庭神经鞘瘤患者听力损失的风险因素的临界点。
在 MEDLINE/PubMed、EMBASE、Web of Science、LILACS/VHL 和 Cochrane 图书馆数据库中，对文献进行了系统的综述，没有语言或出版年限的限制。符合以下标准的研究被纳入：1）人群：接受放射外科治疗前庭神经鞘瘤的成年男女；2）暴露：耳蜗辐射；3）结局：听力损失；4）研究类型：队列。两名独立的审查员进行了整个审查过程。PROSPERO 的注册号为 CRD42020206128。
在搜索中确定了 333 篇文章，经过资格标准筛选后有 7 篇被纳入。纳入的研究中没有关于如何测量暴露或结局的标准化，而且大多数研究没有提供足够的数据进行荟萃分析。
无法确定可被认为是听力损失风险因素的高耳蜗剂量临界点。
