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CRISPR 影响共生关系。

CRISPR-influenced symbiosis.

机构信息

Center for Life in Extreme Environments, Biology Department, Portland State University, Portland, OR, USA.

Biochemistry and Molecular Biology, Genetics and Microbiology, University of Georgia, Athens, GA, USA.

出版信息

Nat Microbiol. 2023 Sep;8(9):1611-1612. doi: 10.1038/s41564-023-01445-4.

DOI:10.1038/s41564-023-01445-4
PMID:37580593
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10791070/
Abstract

CRISPR systems canonically confer microorganisms with protection against invading viral DNA, plasmids and mobile genetic elements, however a multi-omics investigation of deep subsurface archaeal communities suggests that archaeal CRISPR systems might target other archaeal parasites or force a transition from parasitism to mutualism.

摘要

CRISPR 系统通常使微生物免受入侵的病毒 DNA、质粒和可移动遗传元件的侵害,但对深层地下古菌群落的多组学研究表明,古菌 CRISPR 系统可能针对其他古菌寄生虫,或迫使从寄生关系转变为共生关系。

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本文引用的文献

1
A predicted CRISPR-mediated symbiosis between uncultivated archaea.一种预测的 CRISPR 介导的未培养古菌共生关系。
Nat Microbiol. 2023 Sep;8(9):1619-1633. doi: 10.1038/s41564-023-01439-2. Epub 2023 Jul 27.
2
Evolutionary plasticity and functional versatility of CRISPR systems.CRISPR 系统的进化可塑性和功能多样性。
PLoS Biol. 2022 Jan 5;20(1):e3001481. doi: 10.1371/journal.pbio.3001481. eCollection 2022 Jan.
3
CRISPR-Cas Systems and the Paradox of Self-Targeting Spacers.CRISPR-Cas系统与自我靶向间隔序列的悖论
Front Microbiol. 2020 Jan 22;10:3078. doi: 10.3389/fmicb.2019.03078. eCollection 2019.
4
Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants.CRISPR-Cas 系统的进化分类:Class 2 及其衍生变体的爆发。
Nat Rev Microbiol. 2020 Feb;18(2):67-83. doi: 10.1038/s41579-019-0299-x. Epub 2019 Dec 19.
5
Genomic diversity, lifestyles and evolutionary origins of DPANN archaea.DPANN 古菌的基因组多样性、生活方式和进化起源。
FEMS Microbiol Lett. 2019 Jan 1;366(2). doi: 10.1093/femsle/fnz008.
6
Friendly Fire: Biological Functions and Consequences of Chromosomal Targeting by CRISPR-Cas Systems.误击:CRISPR-Cas系统对染色体靶向的生物学功能及后果
J Bacteriol. 2016 Apr 28;198(10):1481-6. doi: 10.1128/JB.00086-16. Print 2016 May 15.
7
Cas9 function and host genome sampling in Type II-A CRISPR-Cas adaptation.II-A型CRISPR-Cas适应性免疫中的Cas9功能与宿主基因组采样
Genes Dev. 2015 Feb 15;29(4):356-61. doi: 10.1101/gad.257550.114.
8
CRISPR loci reveal networks of gene exchange in archaea.CRISPR 基因座揭示了古菌中基因交换的网络。
Biol Direct. 2011 Dec 21;6(1):65. doi: 10.1186/1745-6150-6-65.