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Specialization determines outcomes in inflammation and cancer.

作者信息

Sica Antonio, Lazzeri Massimo

机构信息

Department of Pharmaceutical Sciences, University of Piemonte Orientale 'A. Avogadro', Novara, Italy.

Humanitas Clinical and Research Center, Istituto di Ricovero e Cura a Carattere Scientifico, Rozzano, Milan, Italy.

出版信息

Nat Immunol. 2023 Sep;24(9):1399-1401. doi: 10.1038/s41590-023-01592-0.

DOI:10.1038/s41590-023-01592-0
PMID:37580608
Abstract
摘要

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Inflammation and cancer: molecular mechanisms and clinical consequences.炎症与癌症:分子机制及临床后果
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Heme catabolism and heme oxygenase-1-expressing myeloid cells in pathophysiology.血红素代谢与血红素氧合酶-1 表达的髓系细胞在病理生理学中的作用。

本文引用的文献

1
Physiology and diseases of tissue-resident macrophages.组织驻留巨噬细胞的生理学和疾病。
Nature. 2023 Jun;618(7966):698-707. doi: 10.1038/s41586-023-06002-x. Epub 2023 Jun 21.
2
Macrophages as tools and targets in cancer therapy.巨噬细胞作为癌症治疗的工具和靶点。
Nat Rev Drug Discov. 2022 Nov;21(11):799-820. doi: 10.1038/s41573-022-00520-5. Epub 2022 Aug 16.
3
Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC cells.组织驻留巨噬细胞为早期 NSCLC 细胞提供促肿瘤发生的生态位。
Front Immunol. 2024 Oct 24;15:1433113. doi: 10.3389/fimmu.2024.1433113. eCollection 2024.
Nature. 2021 Jul;595(7868):578-584. doi: 10.1038/s41586-021-03651-8. Epub 2021 Jun 16.
4
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies.采用联合免疫疗法治疗免疫热、改变和冷肿瘤的方法。
Nat Rev Drug Discov. 2019 Mar;18(3):197-218. doi: 10.1038/s41573-018-0007-y.
5
Epigenetics in Cardiac Fibrosis: Emphasis on Inflammation and Fibroblast Activation.心脏纤维化中的表观遗传学:着重于炎症和成纤维细胞激活。
JACC Basic Transl Sci. 2018 Nov 12;3(5):704-715. doi: 10.1016/j.jacbts.2018.05.003. eCollection 2018 Oct.
6
Chronic pancreatitis.慢性胰腺炎。
Nat Rev Dis Primers. 2017 Sep 7;3:17060. doi: 10.1038/nrdp.2017.60.
7
The biology and function of fibroblasts in cancer.成纤维细胞在癌症中的生物学和功能。
Nat Rev Cancer. 2016 Aug 23;16(9):582-98. doi: 10.1038/nrc.2016.73.
8
RORC1 Regulates Tumor-Promoting "Emergency" Granulo-Monocytopoiesis.RORC1 调控肿瘤促进的“紧急”粒单系造血。
Cancer Cell. 2015 Aug 10;28(2):253-69. doi: 10.1016/j.ccell.2015.07.006.
9
Macrophage plasticity and polarization: in vivo veritas.巨噬细胞的可塑性和极化:体内的真实情况。
J Clin Invest. 2012 Mar;122(3):787-95. doi: 10.1172/JCI59643. Epub 2012 Mar 1.
10
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB.耐受性与M2(替代性)巨噬细胞极化是由p50核因子κB精心调控的相关过程。
Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14978-83. doi: 10.1073/pnas.0809784106. Epub 2009 Aug 17.