Lange Tim, Knöchelmann Anne Caroline, Bremer Michael
Klinik für Strahlentherapie und Spezielle Onkologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625, Hannover, Deutschland.
Radiologie (Heidelb). 2023 Sep;63(9):693-702. doi: 10.1007/s00117-023-01198-5.
Adjuvant radiotherapy is an integral part of multimodal therapy for early breast cancer. It contributes to the reduction of local recurrences across all disease stages. (Moderate) hypofractionated whole-breast irradiation is the standard of care. In low-risk situations, partial breast irradiation can be an option. The indication for adjuvant radiotherapy after mastectomy or additional irradiation of regional lymph nodes depends on the patient's individual risk profile. Long-term results of treatment and further development of irradiation techniques now allow shorter, individualized and well-tolerated treatments with the aim of therapy de-escalation.
辅助放疗是早期乳腺癌多模式治疗的一个组成部分。它有助于降低所有疾病阶段的局部复发率。(中等程度)大分割全乳照射是标准治疗方案。在低风险情况下,部分乳腺照射可以作为一种选择。乳房切除术后辅助放疗或区域淋巴结额外照射的适应症取决于患者的个体风险状况。治疗的长期结果以及放疗技术的进一步发展,现在使得能够进行更短、个性化且耐受性良好的治疗,以期实现治疗降级。