Greco A V, Altomonte L, Ghirlanda G, Manna R, Bertoli A
Exp Clin Endocrinol. 1986 Jul;87(2):223-6. doi: 10.1055/s-0029-1210549.
The principal sites of gastrin production in man are localized at the level of the gastric antrum; both the oral glucose load and the protein meal stimulate the gastrin secretion. The aim of this study was to verify the gastrin response in patients with gastric resections presented with various stimuli. In the operated patients, the behavior of serum gastrin after a protein meal was different with respect to that observed in control subjects. After glucose, on the contrary, a very similar result was seen when compared to controls. The increase in serum gastrin of patients with Billroth II provides a further confirmation of an extragastric origin of gastrin.
人体内胃泌素产生的主要部位位于胃窦水平；口服葡萄糖负荷和蛋白质餐均可刺激胃泌素分泌。本研究的目的是验证接受不同刺激的胃切除患者的胃泌素反应。在接受手术的患者中，蛋白质餐后血清胃泌素的变化与对照组观察到的情况不同。相反，在给予葡萄糖后，与对照组相比观察到非常相似的结果。毕罗Ⅱ式手术患者血清胃泌素的升高进一步证实了胃泌素的胃外来源。
