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感觉性大脑皮层的实际范围是由外周神经支配密度决定的吗?

Is areal extent in sensory cerebral cortex determined by peripheral innervation density?

作者信息

Welker E, Van der Loos H

出版信息

Exp Brain Res. 1986;63(3):650-4. doi: 10.1007/BF00237487.

DOI:10.1007/BF00237487
PMID:3758273
Abstract

The whisker-to-barrel pathway of mice (an important component of the animal's somatosensory system) was studied in two experiments. In one, the cortical representation of a row of whiskers was caused to be larger by lesioning a neighbouring row of follicles, while the innervation density remained unchanged. In the second experiment mice, selectively bred for particular whisker and barrel patterns, showed for their supernumerary vibrissal follicles a relatively large cortical representation. On the basis of the second experiment we formulate a possible role of the sensory periphery in brain evolution.

摘要

在两项实验中对小鼠的触须到桶状结构通路(动物体感系统的一个重要组成部分)进行了研究。在其中一项实验中,通过损伤相邻一排毛囊使一排触须的皮质表征变大,而神经支配密度保持不变。在第二项实验中,针对特定触须和桶状模式进行选择性培育的小鼠,其多余的触须毛囊显示出相对较大的皮质表征。基于第二项实验,我们阐述了感觉外周在大脑进化中的一种可能作用。

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1
Is areal extent in sensory cerebral cortex determined by peripheral innervation density?感觉性大脑皮层的实际范围是由外周神经支配密度决定的吗?
Exp Brain Res. 1986;63(3):650-4. doi: 10.1007/BF00237487.
2
Quantitative correlation between barrel-field size and the sensory innervation of the whiskerpad: a comparative study in six strains of mice bred for different patterns of mystacial vibrissae.桶状皮层区域大小与触须垫感觉神经支配之间的定量相关性:对六种为不同触须模式培育的小鼠品系的比较研究。
J Neurosci. 1986 Nov;6(11):3355-73. doi: 10.1523/JNEUROSCI.06-11-03355.1986.
3
Functional organization of mouse and rat SmI barrel cortex following vibrissal damage on different postnatal days.不同出生后天数的触须损伤后小鼠和大鼠体感桶状皮层的功能组织
Somatosens Res. 1984;1(3):207-45. doi: 10.3109/07367228409144548.
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Plasticity of cerebral metabolic whisker maps in adult mice after whisker follicle removal--I. Modifications in barrel cortex coincide with reorganization of follicular innervation.成年小鼠毛囊去除后大脑代谢晶须图谱的可塑性——I. 桶状皮层的改变与毛囊神经支配的重组相一致。
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Partial denervation of the whiskerpad in adult mice: altered patterns of metabolic activity in barrel cortex.成年小鼠触须垫部分去神经支配:桶状皮层代谢活动模式的改变
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Sensorimotor corticocortical projections from rat barrel cortex have an anisotropic organization that facilitates integration of inputs from whiskers in the same row.来自大鼠桶状皮层的感觉运动皮层间投射具有各向异性组织,这有助于整合来自同一排触须的输入信息。
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Use-dependent plasticity in barrel cortex: intrinsic signal imaging reveals functional expansion of spared whisker representation into adjacent deprived columns.桶状皮层的使用依赖可塑性:内在信号成像揭示了保留的触须表征向相邻剥夺柱的功能扩展。
Somatosens Mot Res. 2005 Mar-Jun;22(1-2):25-35. doi: 10.1080/08990220500084990.

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Does the skin tell the somatosensory cortex how to construct a map of the periphery?皮肤会告诉躯体感觉皮层如何构建外周地图吗?
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Mouse somatosensory cortex: alterations in the barrelfield following receptor injury at different early postnatal ages.小鼠体感皮层:不同出生后早期年龄受体损伤后桶状区的改变。
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Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentation.成年猴子在限制性去传入后体感皮层3b区和1区的地形重组
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Functional organization of mouse and rat SmI barrel cortex following vibrissal damage on different postnatal days.不同出生后天数的触须损伤后小鼠和大鼠体感桶状皮层的功能组织
Somatosens Res. 1984;1(3):207-45. doi: 10.3109/07367228409144548.
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Variation in pattern of mystacial vibrissae in mice. A quantitative study of ICR stock and several inbred strains.小鼠口鼻触须模式的变异。对ICR种群和几种近交系的定量研究。
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The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units.小鼠大脑皮层体感区(SI)IV层的结构组织。对由离散细胞构筑单位组成的皮质区域的描述。
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