Lebedev A A, Matveeva A K, Munina I I, Pleshakov M G
Farmakol Toksikol. 1986 Jul-Aug;49(4):46-9.
Experiments on mice, rats and dogs showed that furosemide manufactured in the USSR is not inferior by its specific activity to furosemide manufactured abroad. Furosemide manufactured in the USSR and furosemide-substance made in Finland were compared at three doses--1, 5 and 25 mg/kg. The bioavailability of furosemide tablets manufactured in the USSR and that of "Polfa" production tablets studied on rats (5 and 25 mg/kg) and dogs (40 mg) appeared to be identical.
对小鼠、大鼠和狗进行的实验表明，苏联生产的呋塞米在比活性方面并不逊色于国外生产的呋塞米。将苏联生产的呋塞米与芬兰生产的呋塞米原料药在1、5和25毫克/千克这三种剂量下进行了比较。对大鼠（5和25毫克/千克）和狗（40毫克）研究发现，苏联生产的呋塞米片剂与“Polfa”生产的片剂的生物利用度似乎相同。
