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温泉溺水导致的严重高钙血症

Severe Hypercalcemia due to Drowning in an Onsen (Hot Spring).

作者信息

Ueno Daisuke, Shiino Yasukazu, Takahashi Jiro, Inoue Takahiro

机构信息

Department of Acute Medicine, Kawasaki Medical School, Kurashiki, Japan.

出版信息

J Emerg Trauma Shock. 2023 Apr-Jun;16(2):63-65. doi: 10.4103/jets.jets_78_22. Epub 2023 Feb 24.

DOI:10.4103/jets.jets_78_22
PMID:37583384
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10424746/
Abstract

Hypercalcemia is generally caused by primary hyperparathyroidism, malignancies, and drugs. Herein, we report a case of severe hypercalcemia due to drowning in hot springs. A 55-year-old woman was found floating in a public bath at a hotel and was admitted to a nearby hospital. The patient was intubated because of hypoxia and shock, and noradrenaline was titrated. Computed tomography revealed bilateral aspiration pneumonia. Blood tests revealed hypercalcemia (serum total calcium [Ca]: 18.7 mg/dL). Hyperparathyroidism, malignancy, and drug-related factors were ruled out as the causes of hypercalcemia. In addition, the public bath in which the patient drowned contained high concentrations of Ca. We concluded that the reason for hypercalcemia was accidental ingestion of the hot spring water containing a high concentration of Ca through the gastrointestinal tract. In the case of drowning and hypercalcemia, the cause may be clarified by examining the components that were accidentally swallowed.

摘要

高钙血症通常由原发性甲状旁腺功能亢进、恶性肿瘤和药物引起。在此,我们报告一例因浸泡温泉溺水导致严重高钙血症的病例。一名55岁女性被发现漂浮在酒店的公共浴池里,随后被送往附近医院。患者因缺氧和休克接受气管插管,并滴定去甲肾上腺素。计算机断层扫描显示双侧吸入性肺炎。血液检查显示高钙血症(血清总钙[Ca]:18.7mg/dL)。排除了甲状旁腺功能亢进、恶性肿瘤和药物相关因素作为高钙血症的病因。此外,患者溺水的公共浴池含有高浓度的钙。我们得出结论,高钙血症的原因是通过胃肠道意外摄入了含有高浓度钙的温泉水。对于溺水和高钙血症的情况,通过检查意外吞咽的成分可能会明确病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9616/10424746/cbe5d3f109f3/JETS-16-63-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9616/10424746/cbe5d3f109f3/JETS-16-63-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9616/10424746/cbe5d3f109f3/JETS-16-63-g001.jpg

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本文引用的文献

1
Hypercalcemic crisis resulting from near drowning in an indoor public bath.室内公共浴场溺水导致的高钙血症危象
Am J Case Rep. 2013 Jun 19;14:210-2. doi: 10.12659/AJCR.889279. Print 2013.
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Severe hypercalcemia and polyuria in a near-drowning victim.
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Hypercalcemia complicating an industrial near-drowning.高钙血症并发工业性近溺水事故。
Ann Emerg Med. 1991 Jun;20(6):669-71. doi: 10.1016/s0196-0644(05)82392-3.