Vásquez Loarte Tania, Piña Reyna Yigal, Peña Duque Marco, Ortiz Zegarra César Antonio
Universidad de San Martín de Porras, Lima, Perú. Universidad de San Martín de Porres Universidad de San Martín de Porras Lima Peru.
Instituto Nacional de Cardiología «Ignacio Chávez», Ciudad de México, México. Instituto Nacional de Cardiología «Ignacio Chávez Ciudad de México México.
Arch Peru Cardiol Cir Cardiovasc. 2023 Mar 31;4(1):7-12. doi: 10.47487/apcyccv.v4i1.282. eCollection 2023 Jan-Mar.
To evaluate the degree of incomplete revascularization in patients with multiarterial coronary artery disease who underwent percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) using the Syntax revascularization index (SRI) and its relationship to major cardiovascular events during follow-up.
Observational, retrospective study with 4-year follow-up of patients with multiarterial coronary artery disease who underwent surgical or percutaneous coronary revascularization, in whom the baseline Syntax score (SSb) and the residual Syntax score (SSr) were calculated. The Syntax Revascularization Index (SRI) was determined with the following formula: SRI = (1- [SSr/SSb]) x 100, and major cardiovascular events at 4-year follow-up were compared.
Two hundred patients (100 in each group) were evaluated. Mean SSr in group 1 was 83.2%, and in group 2, 79.0% (p=0.88). Mean complete revascularization was 41% in the first group and 35% in the second. A cutoff point of ≤90% of IRS had the best accuracy for predicting major cardiovascular events (area under the curve of 0.60; 95% CI: 0.49-0.71, p<0.05). In multivariate analysis IRS was an independent predictor of major cardiovascular events (HR 2.6; 95%CI: 1.32-3.22, p= 0.043).
The Syntax Revascularization Index may be useful for measuring the degree of revascularization in patients with multiarterial coronary artery disease treated percutaneously or surgically. An SRI ³90% may be an acceptable target for revascularization
使用Syntax血运重建指数（SRI）评估接受经皮冠状动脉介入治疗（PCI）或冠状动脉旁路移植术（CABG）的多支冠状动脉疾病患者的不完全血运重建程度及其与随访期间主要心血管事件的关系。
对接受外科或经皮冠状动脉血运重建的多支冠状动脉疾病患者进行为期4年的观察性回顾性研究，计算其基线Syntax评分（SSb）和残余Syntax评分（SSr）。Syntax血运重建指数（SRI）通过以下公式确定：SRI =（1 - [SSr/SSb]）×100，并比较4年随访时的主要心血管事件。
评估了200例患者（每组100例）。第1组的平均SSr为83.2%，第2组为79.0%（p = 0.88）。第一组的平均完全血运重建率为41%，第二组为35%。IRS≤90%的截断点对预测主要心血管事件具有最佳准确性（曲线下面积为0.60；95%CI：0.49 - 0.71，p < 0.05）。在多变量分析中，IRS是主要心血管事件的独立预测因素（HR 2.6；95%CI：1.32 - 3.22，p = 0.043）。
Syntax血运重建指数可能有助于衡量经皮或手术治疗的多支冠状动脉疾病患者的血运重建程度。SRI≥90%可能是血运重建的可接受目标。
