Tijssen Janice A, McClean Marisha, Lam Melody, Le Britney, To Teresa
Schulich School of Medicine and Dentistry, Western University, Canada.
Department of Paediatrics, London Health Sciences Centre, London, Canada.
Resusc Plus. 2023 Aug 5;15:100442. doi: 10.1016/j.resplu.2023.100442. eCollection 2023 Sep.
There are no Canadian epidemiological studies of Paediatric Out-of-Hospital Cardiac Arrest (POHCA) for ≥20 years. Understanding the epidemiology of POHCA is key to prevention, education, and management strategies.
We applied a validated algorithm to hospital administrative databases to describe paediatric (age 1 day to ≤18 years) atraumatic OHCA in Ontario from 2004-2020.
The cohort included 1,839 paediatric patients with atraumatic POHCA occurring at a median (IQR) age of 2 (0-12) years with 721 (39.2%) POHCA events in <1-year-olds. Males accounted for 71.1% ( = 1123) of the cohort. Crude incidence of children with POHCA who were transported to an Emergency Department was 4.2/100,000 with an increase annually over the study period ( = 0.0065). Thirty percent ( = 560) lived in a neighbourhood with the lowest income quintile, while 13.6% ( = 251) lived in a neighbourhood with the highest income quintile, 78.6% ( = 1444) presented to a non-academic hospital, and the majority ( = 1533, 83.4%) did not have significant comorbidities. Survival to hospital discharge was achieved in 167 (9.1%). Less than 6 (<3.6%) patients had a repeat POHCA in the year following the index event.
This is the largest Canadian POHCA cohort and the first to describe its incidence, comorbidities, and sociodemographic characteristics. We found an increase in annual crude incidence, POHCA mostly occurred in healthy children, and survival was similar to other cohorts. There were more than double the number of POHCA events in children living in the lowest income quintile neighborhoods compared to the highest. Most children presented to non-academic hospitals first.
加拿大尚无关于20年及以上儿童院外心脏骤停(POHCA)的流行病学研究。了解POHCA的流行病学是预防、教育和管理策略的关键。
我们将一种经过验证的算法应用于医院行政数据库,以描述2004年至2020年安大略省儿童(年龄1天至≤18岁)非创伤性院外心脏骤停情况。
该队列包括1839例儿童非创伤性POHCA患者,中位(IQR)年龄为2岁(0至12岁),其中721例(39.2%)POHCA事件发生在1岁以下儿童中。男性占队列的71.1%(n = 1123)。被转运至急诊科的POHCA儿童的粗发病率为4.2/10万,在研究期间呈逐年上升趋势(p = 0.0065)。30%(n = 560)居住在收入最低五分位数的社区,而13.6%(n = 251)居住在收入最高五分位数的社区,78.6%(n = 1444)被送往非学术性医院,且大多数(n = 1533,83.4%)没有严重合并症。167例(9.1%)存活至出院。在首次事件发生后的一年内,少于6例(<3.6%)患者再次发生POHCA。
这是加拿大最大的POHCA队列,也是首个描述其发病率、合并症及社会人口学特征的队列。我们发现年粗发病率上升,POHCA大多发生在健康儿童中,且存活率与其他队列相似。与收入最高五分位数社区的儿童相比,收入最低五分位数社区儿童的POHCA事件数量多出一倍多。大多数儿童首先被送往非学术性医院。