Kaffka Genaamd Dengler S E, Vervoorn M T, Brouwer M, de Jonge J, van der Kaaij N P
Department of Cardiothoracic Surgery, University Medical Center Utrecht, Utrecht, Netherlands.
Department of Surgery, Erasmus Medical Center Transplant Institute, Rotterdam, Netherlands.
Front Cardiovasc Med. 2023 Jul 31;10:1225543. doi: 10.3389/fcvm.2023.1225543. eCollection 2023.
With an expanding population at risk for heart failure and the resulting increase in patients admitted to the waiting list for heart transplantation, the demand of viable organs exceeds the supply of suitable donor hearts. Use of hearts after circulatory death has reduced this deficit. Two primary techniques for heart procurement in circulatory death donors have been described: direct procurement and perfusion and thoraco-abdominal normothermic regional perfusion. While the former has been accepted as an option for heart procurement in circulatory death donors, the latter technique has raised some ethical questions in relation to the dead donor rule. In this paper we discuss the current dilemmas regarding these heart procurement protocols in circulatory death donors.
随着心力衰竭风险人群的不断增加，导致心脏移植等待名单上的患者数量上升，可用器官的需求超过了合适供体心脏的供应。使用循环死亡后的心脏减少了这一缺口。已经描述了循环死亡供体心脏获取的两种主要技术：直接获取与灌注以及胸腹常温区域灌注。虽然前者已被接受为循环死亡供体心脏获取的一种选择，但后一种技术在与死亡供体规则相关方面引发了一些伦理问题。在本文中，我们讨论了关于循环死亡供体这些心脏获取方案的当前困境。
