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利用循环性死亡后供体的成人心脏移植。

Adult cardiac transplantation utilizing donors after circulatory death.

作者信息

Rajah Tanisha, Blitzer David, Silvestry Scott, Copeland Hannah

机构信息

Birmingham Medical School, University of Birmingham, Birmingham, UK.

Division of Cardiac, Thoracic, and Vascular Surgery, Department of Surgery, New York Presbyterian-Columbia University Irving Medical Center, New York, NY, USA.

出版信息

Ann Cardiothorac Surg. 2024 Nov 30;13(6):474-486. doi: 10.21037/acs-2024-dcd-0069. Epub 2024 Aug 23.

Abstract

Donation after circulatory death (DCD) presents both opportunities and challenges in the realm of heart transplantation. Its emergence holds promise for narrowing the gap between patients in need of organs and the available donor pool. The rapid emergence of DCD use has allowed heart transplant volume to increase worldwide. Long-term outcomes and best practices remain to be defined and are important considerations in the wider use of these techniques in a broad selection of patients to understand best use and practice moving forward. Expanding DCD donation entails substantial resource allocation, coordination efforts, and training initiatives. Moving forward, standardization is imperative, particularly in aspects such as "stand-off" time, warm ischemic time (WIT), and perfusate composition.

摘要

心脏死亡后器官捐献(DCD)在心脏移植领域既带来了机遇,也带来了挑战。它的出现有望缩小器官需求患者与可用供体库之间的差距。DCD的迅速应用使全球心脏移植数量得以增加。长期结果和最佳实践仍有待确定,这是在广泛的患者中更广泛地使用这些技术时需要考虑的重要因素,以便了解未来的最佳使用方法和实践。扩大DCD捐献需要大量的资源分配、协调工作和培训计划。展望未来,标准化至关重要,尤其是在“等待”时间、热缺血时间(WIT)和灌注液成分等方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9e5b/11618117/5dcb63a5bb12/acs-13-06-474-f1.jpg

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