• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

改良圣托马斯溶液预处理严重上肢损伤患者:四例报告

Pretreatment with a modified St. Thomas' solution in patients with severe upper limb injuries: Four case reports.

作者信息

Sun Zhong-Yang, Li Li-Yi, Xing Jian-Xin, Tong Liang-Cheng, Li Ying

机构信息

Department of Orthopedics, Air Force Hospital of Eastern Theater, Nanjing 210002, Jiangsu Province, China.

出版信息

World J Clin Cases. 2023 Jul 16;11(20):4926-4931. doi: 10.12998/wjcc.v11.i20.4926.

DOI:10.12998/wjcc.v11.i20.4926
PMID:37583986
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10424047/
Abstract

BACKGROUND

This study aims to describe the application of a modified St. Thomas' solution in patients with severe limb injuries.

CASE SUMMARY

Four patients who sustained a high-energy trauma and underwent complete upper limb amputation were pretreated with a modified St. Thomas' solution before upper limb replantation. After the perfusion solution stopped flowing from the blood vessel, the amputated upper limb amputation was replanted. The patients were instructed to perform functional rehabilitation training after the operation. All 4 patients were followed up for 5 years. All the severed upper limbs survived. Routine re-examination after the operation showed that the function of the affected limb was restored. All the patients were satisfied with the sensory and functional recovery of the affected limb.

CONCLUSION

The modified St. Thomas' solution can effectively improve the success rate of limb salvage surgery and the recovery of limb function in patients with a severe limb injury.

摘要

背景

本研究旨在描述改良圣托马斯溶液在严重肢体损伤患者中的应用。

病例摘要

4例遭受高能创伤并接受上肢完全截肢的患者在进行上肢再植术前接受了改良圣托马斯溶液预处理。当灌注液停止从血管流出后,对截断的上肢进行再植。术后指导患者进行功能康复训练。4例患者均随访5年。所有离断的上肢均存活。术后常规复查显示患侧肢体功能恢复。所有患者对患侧肢体的感觉和功能恢复均满意。

结论

改良圣托马斯溶液可有效提高严重肢体损伤患者保肢手术的成功率及肢体功能恢复情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1685/10424047/771de98f740f/WJCC-11-4926-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1685/10424047/771de98f740f/WJCC-11-4926-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1685/10424047/771de98f740f/WJCC-11-4926-g001.jpg

相似文献

1
Pretreatment with a modified St. Thomas' solution in patients with severe upper limb injuries: Four case reports.改良圣托马斯溶液预处理严重上肢损伤患者:四例报告
World J Clin Cases. 2023 Jul 16;11(20):4926-4931. doi: 10.12998/wjcc.v11.i20.4926.
2
Comparison of UW solution and St. Thomas' solution in the rat: importance of potassium concentration.UW液与圣托马斯液在大鼠中的比较:钾浓度的重要性。
Ann Thorac Surg. 1996 Feb;61(2):576-84. doi: 10.1016/0003-4975(95)01085-8.
3
The effectiveness of University of Wisconsin solution on prolonged myocardial protection as assessed by phosphorus 31-nuclear magnetic resonance spectroscopy and functional recovery.通过磷31核磁共振波谱法和功能恢复评估威斯康星大学溶液在延长心肌保护方面的有效性。
J Thorac Cardiovasc Surg. 1992 Nov;104(5):1356-64.
4
A clinical comparative study between crystalloid and blood-based St Thomas' hospital cardioplegic solution.晶体与基于血液的圣托马斯医院心脏停搏液的临床对比研究。
Eur J Cardiothorac Surg. 1999 Jan;15(1):75-83. doi: 10.1016/s1010-7940(98)00287-5.
5
Calcium content of St. Thomas' II cardioplegic solution damages ischemic immature myocardium.
Ann Thorac Surg. 1991 Oct;52(4):993-9. doi: 10.1016/0003-4975(91)91266-x.
6
Lowering the calcium concentration in St. Thomas' Hospital cardioplegic solution improves protection during hypothermic ischemia.降低圣托马斯医院心脏停搏液中的钙浓度可改善低温缺血期间的心肌保护作用。
J Thorac Cardiovasc Surg. 1991 Feb;101(2):314-25.
7
Prevention of cell swelling with low chloride St. Thomas' Hospital solution improves postischemic myocardial recovery.
J Thorac Cardiovasc Surg. 1998 May;115(5):1196-202. doi: 10.1016/S0022-5223(98)70421-0.
8
Validity of a model of cultured myocardial cells for assessment of cardioplegia.用于评估心脏停搏液的培养心肌细胞模型的有效性
Cell Biol Toxicol. 1997 Oct;13(6):435-44. doi: 10.1023/a:1007471827543.
9
Superior qualities of University of Wisconsin solution for ex vivo preservation of the pig heart.威斯康星大学溶液用于猪心脏离体保存的卓越品质。
J Thorac Cardiovasc Surg. 1992 Aug;104(2):229-40.
10
Hypothermic preservation of isolated rat lungs in modified bicarbonate buffer, EuroCollins solution or St Thomas' Hospital cardioplegic solution.在改良碳酸氢盐缓冲液、EuroCollins溶液或圣托马斯医院心脏停搏液中对离体大鼠肺进行低温保存。
Eur J Cardiothorac Surg. 1998 Nov;14(5):508-15. doi: 10.1016/s1010-7940(98)00188-2.

本文引用的文献

1
PPARγ in Ischemia-Reperfusion Injury: Overview of the Biology and Therapy.过氧化物酶体增殖物激活受体γ在缺血再灌注损伤中的作用:生物学与治疗概述
Front Pharmacol. 2021 Apr 28;12:600618. doi: 10.3389/fphar.2021.600618. eCollection 2021.
2
Del Nido Cardioplegia in Coronary Artery Bypass Grafting Surgery: A safe, efficacious and economic alternative to St. Thomas solution; an experience from a developing nation.冠状动脉搭桥手术中使用德尔尼多心脏停搏液:一种安全、有效且经济的替代圣托马斯溶液的方法;来自一个发展中国家的经验。
Perfusion. 2021 Jul;36(5):470-475. doi: 10.1177/0267659121991033. Epub 2021 Jan 28.
3
Skeletal muscle in health and disease.
健康与疾病中的骨骼肌
Dis Model Mech. 2020 Feb 6;13(2):dmm042192. doi: 10.1242/dmm.042192.
4
Emergency Repair of Severe Limb Injuries With Free Flow-Through Chimeric Anterolateral Thigh Perforator Flap.应用游离穿支嵌合股前外侧皮瓣急诊修复严重肢体损伤
Ann Plast Surg. 2019 Dec;83(6):670-675. doi: 10.1097/SAP.0000000000001913.
5
Effects of ischemic preconditioning protocols on skeletal muscle ischemia-reperfusion injury.缺血预处理方案对骨骼肌缺血再灌注损伤的影响。
J Surg Res. 2015 Feb;193(2):942-52. doi: 10.1016/j.jss.2014.09.032. Epub 2014 Sep 30.
6
Addition of tanshinone IIA to UW solution decreases skeletal muscle ischemia-reperfusion injury.在UW溶液中添加丹参酮IIA可减轻骨骼肌缺血再灌注损伤。
Acta Pharmacol Sin. 2006 Aug;27(8):991-9. doi: 10.1111/j.1745-7254.2006.00357.x.
7
Preservation of rat cremaster muscle microcirculation after prolonged cold storage and transplantation.长时间冷藏及移植后大鼠提睾肌微循环的保存
J Surg Res. 2006 Mar;131(1):41-8. doi: 10.1016/j.jss.2005.05.027. Epub 2005 Aug 1.
8
Effects of systemic and regional taurine on skeletal muscle function following ischaemia-reperfusion injury.全身和局部应用牛磺酸对缺血再灌注损伤后骨骼肌功能的影响。
J Orthop Res. 2005 Mar;23(2):310-4. doi: 10.1016/j.orthres.2004.07.003.
9
Local hypothermia during early reperfusion protects skeletal muscle from ischemia-reperfusion injury.早期再灌注期间的局部低温可保护骨骼肌免受缺血-再灌注损伤。
Plast Reconstr Surg. 2003 Jan;111(1):242-50. doi: 10.1097/01.PRS.0000034936.25458.98.
10
Cold storage of rat skeletal muscle free flaps and pre-ischemic perfusion with modified UW solution.大鼠骨骼肌游离皮瓣的冷藏及用改良UW溶液进行缺血前灌注
Microsurgery. 2000;20(7):343-9. doi: 10.1002/1098-2752(2000)20:7<343::aid-micr6>3.0.co;2-c.